Evidence map›Paper›PMID 29541520›Full record

ArticleBiomedical optics express2018

Change in human lens dimensions, lens refractive index distribution and ciliary body ring diameter with accommodation.

Adnan Khan, James M Pope, Pavan K Verkicharla, Marwan Suheimat, David A Atchison

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 50 citations in OpenAlex.

  1. Influence of Refractive Index of the Crystalline Lens on Optical Biometric Measurements.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  2. Article
  3. Article
  4. Influence of Light Wavelength and Optotype Size on Accommodative Response and Aberrometric Changes Across the Adult Lifespan.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  5. Review
  6. Article
  7. Observational
  8. Article
  9. Accommodating version of a schematic eye for emmetropia and myopia.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The evolution of mechanism of accommodation and a novel hypothesis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Review
  15. Article
  16. An Overview of the Penguin Visual System.Vision (Basel, Switzerland) · 2023
    Review
  17. Article
  18. Article
  19. Article
  20. IMI Accommodation and Binocular Vision in Myopia Development and Progression.Investigative ophthalmology & visual science · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Adnan KhanWeill Cornell Medicine-Qatar, Education City, Qatar Foundation, Doha, Qatar and New York, USA.
James M PopeInstitute of Health & Biomedical Innovation, Queensland University of Technology, Kelvin Grove, QLD, Australia.
Pavan K VerkicharlaInstitute of Health & Biomedical Innovation, Queensland University of Technology, Kelvin Grove, QLD, Australia.
Marwan SuheimatInstitute of Health & Biomedical Innovation, Queensland University of Technology, Kelvin Grove, QLD, Australia.
David A AtchisonInstitute of Health & Biomedical Innovation, Queensland University of Technology, Kelvin Grove, QLD, Australia.
Queensland University of Technology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated changes in ciliary body ring diameter, lens dimensions and lens refractive index distributions with accommodation in young adults. A 3T clinical magnetic resonance imaging scanner imaged right eyes of 38 18-29 year old participants using a multiple spin echo sequence to determine accommodation-induced changes along lens axial and equatorial directions. Accommodation stimuli were approximately 1 D and 5 D. With accommodation, ciliary body ring diameter, and equatorial lens diameter decreased (-0.43 ± 0.31 mm and -0.30 ± 0.23 mm, respectively), and axial lens thickness increased ( + 0.34 ± 0.16 mm). Lens shape changes cause redistribution of the lens internal structure, leading to change in refractive index distribution profiles. With accommodation, in the axial direction refractive index profiles became flatter in the center and steeper near the periphery of the lens, while in the equatorial direction they became steeper in the center and flatter in the periphery. The results suggest that the anatomical accuracy of lens optical models can be improved by accounting for changes in the refractive index profile during accommodation.

Indexed as

(170.3890) Medical optics instrumentation(330.4875) Optics of physiological systems(330.7322) Visual optics, accommodation

Identifiers

PMID29541520
PMCPMC5846530
OpenAlexW2788834242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.