Evidence map›Paper›PMID 29541502›Full record

ArticleBiomedical optics express2018

Development of a universal, tunable, miniature fluorescence microscope for use at the point of care.

Cynthia Wong, Michal E Pawlowski, Alessandra Forcucci, Catherine E Majors, Rebecca Richards-Kortum, Tomasz S Tkaczyk

Abstract read
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cynthia WongDepartment of Bioengineering, Rice University, 6500 Main Street, Houston, TX 77005, USA.
Michal E PawlowskiDepartment of Bioengineering, Rice University, 6500 Main Street, Houston, TX 77005, USA.
Alessandra ForcucciDepartment of Bioengineering, Rice University, 6500 Main Street, Houston, TX 77005, USA.
Catherine E MajorsDepartment of Bioengineering, Rice University, 6500 Main Street, Houston, TX 77005, USA.
Rebecca Richards-KortumDepartment of Bioengineering, Rice University, 6500 Main Street, Houston, TX 77005, USA.
Tomasz S TkaczykDepartment of Bioengineering, Rice University, 6500 Main Street, Houston, TX 77005, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluorescence microscopy can be a powerful tool for cell-based diagnostic assays; however, imaging can be time consuming and labor intensive to perform. Tunable systems give the ability to electronically focus at user selected depths inside an object volume and may simplify the opto-mechanical design of the imaging system. We present a prototype of a universal, tunable, miniature fluorescence microscope built from poly(methyl methacrylate) singlets that incorporates miniature, electrowetted lenses for electronic focusing. We demonstrate the ability of this system to perform clinically relevant differential white blood cell counts using single use custom cartridges pre-loaded with the fluorescent dye acridine orange.

Indexed as

(170.1470) Blood or tissue constituent monitoring(170.2520) Fluorescence microscopy(170.3880) Medical and biological imaging

Identifiers

PMID29541502
PMCPMC5846512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.