Evidence map›Paper›PMID 29541387›Full record

ArticleOncotarget2018

DcR3, a new biomarker for sepsis, correlates with infection severity and procalcitonin.

Liqin Gao, Bin Yang, Hairong Zhang, Qishui Ou, Yulan Lin, Mei Zhang, Zhenhuan Zhang, Sunghee Kim, Bing Wu, Zeng Wang and 13 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Diagnostic Potential of Serum Interleukin-6 in Predicting Bacteremia in Adult Patients with Sepsis: A Prospective Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  5. Article
  6. Research Progress of DcR3 in the Diagnosis and Treatment of Sepsis.International journal of molecular sciences · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Biomarkers of sepsis: time for a reappraisal.Critical care (London, England) · 2020
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 4 institutions in 2 countries.

Liqin GaoDepartment of Laboratory Medicine, First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China.
Bin YangDepartment of Laboratory Medicine, First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China.
Hairong ZhangFujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou 350005, China.
Qishui OuDepartment of Laboratory Medicine, First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China.
Yulan LinDepartment of Laboratory Medicine, First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China.
Mei ZhangDepartment of Radiation Oncology, University of Florida, Gainesville, Florida 32610, USA.
Zhenhuan ZhangDepartment of Radiation Oncology, University of Florida, Gainesville, Florida 32610, USA.
Sunghee KimBioPowerTech, Tuscaloosa, Alabama 35406, USA.
Bing WuFujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou 350005, China.
Zeng WangFujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou 350005, China.
Lengxi FuFujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou 350005, China.
Jingan LinFujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou 350005, China.
Ruiqing ChenFujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou 350005, China.
Ruilong LanFujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou 350005, China.
Junying ChenFujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou 350005, China.
Wei ChenFujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou 350005, China.
Long ChenFujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou 350005, China.
Hengshan ZhangFujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou 350005, China.
Deping HanFujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou 350005, China.
Jingrong ChenFujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou 350005, China.
Paul OkunieffDepartment of Radiation Oncology, University of Florida, Gainesville, Florida 32610, USA.
Jianhua LinFujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou 350005, China.
Lurong ZhangFujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou 350005, China.
Fujian Institute of Microbiology · CNFujian Medical University · CNFirst Affiliated Hospital of Fujian Medical University · CNUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early diagnosis of sepsis is critical for successful treatment. The clinical value of DcR3 in early diagnosis of sepsis was determined in a dynamic follow-up study. Alterations in plasma levels of DcR3, PCT, CRP, and IL-6 were measured by ELISA and compared among patients with sepsis (

Indexed as

clinical valuecorrelation with procalcitoninearly diagnosisplasma DcR3sepsis

Identifiers

PMID29541387
PMCPMC5834251
OpenAlexW2775898127

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.