ArticleOxidative medicine and cellular longevity2018
Grape Seed Proanthocyanidin Extract Prevents Ovarian Aging by Inhibiting Oxidative Stress in the Hens.
Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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Who cites it
61 citing papers in PubMed, 125 citations in OpenAlex.
- Effects of Oligomeric Ultrafine-Nano Hydrogen Water on Laying Performance, Egg Quality, Nutrient Composition, and Intestinal and Reproductive Responses in Late-Laying Hens.Animals : an open access journal from MDPI · 2026Article
- Transcriptome sequencing reveals the regulatory mechanisms during the development of small white follicles to small yellow follicles in laying hens.Poultry science · 2026Article
- Integrated analysis of transcriptome and metabolomic uncover molecular mechanisms of ovarian aging in laying hens.Poultry science · 2026Article
- Multi-tissue analysis identifies mitochondrial genes in chicken aging-induced productivity decline.Journal of animal science and biotechnology · 2026Article
- Protective Effect of Glutathione Supplementation On Mouse Ovarian Tissue Vitrification and Autologous Transplantation.Reproductive sciences (Thousand Oaks, Calif.) · 2026Article
- Nutrigenomic evidence of phytogenic cytoprotective functions in the ovary and liver provides mechanistic support for improved laying hen performance.Animal biotechnology · 2025Article
- PINK1 functions in mitophagy and mitochondrial homeostasis during mice oocyte maturation.Cell & bioscience · 2025Article
- The combination of dietary active dry yeast andAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Attenuating Effect of a Polyphenol Ellagic Acid on Ovarian Aging by Inhibiting the Ferroptosis Pathway in Low-Yield Laying Chickens.Antioxidants (Basel, Switzerland) · 2025Article
- Effects of Grape Seed Proanthocyanidins on Growth Performance, Jejunal Antioxidant Capacity, Gut Microbial Diversity, and Metabolites in Kangle Chickens.Animals : an open access journal from MDPI · 2025Article
- Grape Seed Proanthocyanidin Extract Improves Growth Performance and Protects Against Hydrogen Peroxide-Induced Oxidative Stress to the Liver and Intestine in Weaned Hyla Rabbits.Animals : an open access journal from MDPI · 2025Article
- Effects of dietary supplementation with grape seed powders on growth performance and muscle nutrition of grass carp (Frontiers in physiology · 2025Article
- Targeting programmed cell death with natural products: a potential therapeutic strategy for diminished ovarian reserve and fertility preservation.Frontiers in pharmacology · 2025Review
- Marine red yeast supplementation improves laying performance by regulating small intestinal homeostasis in aging chickens.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- Potential mechanism prediction of indole-3-propionic acid against diminished ovarian reserve via network pharmacology, molecular docking and experimental verification.BMC complementary medicine and therapies · 2024Article
- Coccidiosis in Egg-Laying Hens and Potential Nutritional Strategies to Modulate Performance, Gut Health, and Immune Response.Animals : an open access journal from MDPI · 2024Review
- TRIM28-Mediated Excessive Oxidative Stress Induces Cellular Senescence in Granulosa Cells and Contributes to Premature Ovarian Insufficiency In Vitro and In Vivo.Antioxidants (Basel, Switzerland) · 2024Article
- Article
- Differential analysis of ovarian tissue between high and low-yielded laying hens in the late laying stage and the effect of LECT2 gene on follicular granulosa cells proliferation.Molecular biology reports · 2024Article
- Graded levels of Eimeria infection modulated gut physiology and temporarily ceased the egg production of laying hens at peak production.Poultry science · 2024Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxidative stress is an important inducement in ovarian aging which results in fecundity decline in human and diverse animals. As a potent antioxidant, grape seed proanthocyanidin extract (GSPE) was investigated to ameliorate chicken ovarian aging in this study. Firstly, ovarian antioxidant capacity of hens at different ages (90, 150, 280, and 580 days old) was compared to elucidate its age-related changes. Subsequently, a D-gal-induced (2.5 mg/mL) aging ovarian model was established and the cultured ovarian tissues were treated with GSPE at 5
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