Evidence map›Paper›PMID 29541152›Full record

ArticleClinical practice and epidemiology in mental health : CP & EMH2018

Design of FRET Probes for SNP RS1006737, Related to Mood Disorder.

Germano Orrù, Mauro Giovanni Carta, Alessia Bramanti

Abstract read
In one paragraph

Article in Clinical practice and epidemiology in mental health : CP & EMH, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Germano OrrùDepartment of Surgical Sciences, Molecular Biology Service (MBS), University of Cagliari, Cagliari, Italy.
Mauro Giovanni CartaDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Alessia BramantiIstituto di Scienze Applicate e Sistemi Intelligenti, ISASI, Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral studies have shown that the Single Nucleotide Polymorphism (SNP) in the CACAN1C gene, rs1006737, is related to different mood disorder illnesses, such as bipolar disorder and schizophrenia. Current day molecular procedures for allele detection of this gene can be very expensive and time consuming. Hence, a sensitive and specific molecular procedure for detecting these mutations in a large number of subjects is desirable, especially for research groups who have no complex laboratory equipment.

objectiveThe possibility of using a Fluorescence Resonance Energy Transfer (FRET) probe was evaluated by means of bioinformatic tools, designed for forecasting the molecular behavior of DNA probes used in the research field or for laboratory analysis methods.

methodIn this study we used the DINAMelt Web Server to predict the

resultsThe molecular probe described in this study detected a

conclusionAlthough

Indexed as

CACNA1C geneFRET probesGenome-wide association studies (GWAS)Mood disordersReal time PCRRS1006737

Identifiers

PMID29541152
PMCPMC5838627

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.