ArticleClinical practice and epidemiology in mental health : CP & EMH2018
Takotsubo Syndrome is Associated with Mood Disorders and Antidepressants Use, not with Anxiety and Impairment of Quality of Life Due to the Psychiatric Disorder.
Article in Clinical practice and epidemiology in mental health : CP & EMH, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Heart rate variability alterations in takotsubo syndrome and related association with psychological factors: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Randomized Controlled Trial of Internet-Delivered Cognitive Behavioral Therapy After Myocardial Infarction With Nonobstructive Coronary Arteries or Takotsubo Syndrome.Journal of the American Heart Association · 2026Trial
- Bridging Minds and Hearts by Exploring the Comorbidities Between Anxiety, Depression, and Takotsubo Cardiomyopathy: A Scoping Review.Journal of clinical medicine · 2026Review
- Various Psychiatric Comorbidities and Smoking Appear to be Associated With Takotsubo Cardiomyopathy: A Nationwide Analysis From 2016 to 2022.Critical pathways in cardiology · 2026Observational
- Long-term outcomes and worse clinical course in Takotsubo syndrome patients with amyotrophic lateral sclerosis.Journal of cardiovascular medicine (Hagerstown, Md.) · 2025Article
- Cardiovascular disease and psychiatric disorders: An-up-to date review.Journal of public health research · 2024Review
- Syncope and Cannabis: hypervagotonia from chronic abuse? A case report and literature review.BMC cardiovascular disorders · 2023Review
- Does Patient Compliance Influence Wearable Cardioverter Defibrillator Effectiveness? A Single-Center Experience.Journal of clinical medicine · 2023Article
- Catecholamine-induced Takotsubo syndrome: a case series.European heart journal. Case reports · 2023Article
- Depression in Heart Failure with Reduced Ejection Fraction, an Undervalued Comorbidity: An Up-To-Date Review.Medicina (Kaunas, Lithuania) · 2023Review
- Management of heart failure: similarities and discrepancies between the European Society of Cardiology and the American Heart Association guidelines.European heart journal supplements : journal of the European Society of Cardiology · 2023Article
- Non-invasive coronary flow velocity reserve assessment predicts adverse outcome in women with unstable angina without obstructive coronary artery stenosis.Journal of public health research · 2023Article
- Psychocardiological assessment in the acute phase of the takotsubo syndrome : Somatic and depressive disorders, resilience and illness perception.Wiener klinische Wochenschrift · 2022Article
- Pre-existing Psychiatric Morbidity Is Strongly Associated to Takotsubo Syndrome: A Case-Control Study.Frontiers in cardiovascular medicine · 2022Article
- Takotsubo Syndrome Associated with a New Onset Manic Episode: A case report.The Journal of international medical research · 2021Article
- Prevalence Estimates, Severity, and Risk Factors of Depressive Symptoms among Coronary Artery Disease Patients after Ten Days of Percutaneous Coronary Intervention.Clinical practice and epidemiology in mental health : CP & EMH · 2021Article
- Review
- Myocardial contrast echocardiography in the diagnosis of postoperative takotsubo myocardiopathy: case report and literature review.BMC cardiovascular disorders · 2019Review
- Takotsubo Syndrome and Electroconvulsive Therapy: Time for Rigorous Assessment.Clinical practice and epidemiology in mental health : CP & EMH · 2019Article
- Traumatic Events, Personality and Psychopathology in Takotsubo Syndrome: A Systematic Review.Frontiers in psychology · 2019Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim was to study the association between mood and anxiety disorders and the Tako-Tsubo Syndrome (TTS) and to determine the role of antidepressants and the impairment of quality of life due the comorbid psychiatric disorder.
methodsCase-control study: 19 consecutive patients (17 female) with TTS compared to 76 controls without TTS, were randomly selected from the database of a nationwide epidemiological study after matching (gender, age and residence) by controls. Psychiatric diagnoses were carried out according to the ICD-10 using semi-structured interview tools (ANTAS-SCID) administered by clinical staff. Quality of Life (Qol) was assessed by means of SF-12.
resultsOnly Major Depressive Disorders (MDD) showed higher frequencies in cases with statistical significance difference (p=0.014) as well as at least one Mood Disorder Diagnosis [MDD or BD] (p=0.002). The lifetime prevalence of at least one anxiety disorder with no comorbid mood disorder did not show a higher frequency in cases (p=0.57).The score at SF-12 in the TTS group was similar to those of controls (p=0.71)In the TTS group, the score at SF-12 in people with one mood or anxiety diagnosis (N=7) was similar to those without mood or anxiety diagnosis (p=0.75). The use of antidepressants was higher in TTS group (15.79% vs 1.31%; p=0.030).
conclusionThe study shows an association between TTS with depressive disorders and antidepressants use and does not confirm the association with anxiety syndromes. The study suggests the need to investigate the possible interactions between antidepressants use and mood disorders in studies with appropriate design and sample size.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.