Evidence map›Paper›PMID 29541070›Full record

ArticleFrontiers in immunology2018

Transcription Factor KLF10 Constrains IL-17-Committed Vγ4

Girak Kim, Min Jeong Gu, Soo Ji Kim, Kwang Hyun Ko, Yoon-Chul Kye, Cheol Gyun Kim, Jae-Ho Cho, Woon-Kyu Lee, Ki-Duk Song, Hyuk Chu and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Girak KimDepartment of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, South Korea.
Min Jeong GuDepartment of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, South Korea.
Soo Ji KimDepartment of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, South Korea.
Kwang Hyun KoDepartment of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, South Korea.
Yoon-Chul KyeDepartment of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, South Korea.
Cheol Gyun KimDepartment of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, South Korea.
Jae-Ho ChoAcademy of Immunology and Microbiology, Institute for Basic Science, Pohang, South Korea.
Woon-Kyu LeeCollege of Medicine, Inha University, Incheon, South Korea.
Ki-Duk SongDepartment of Animal Biotechnology, Chonbuk National University, Jeonju, South Korea.
Hyuk ChuDivision of Bacterial Disease Research, Center for Infectious Disease Research, National Institute of Health, Korea Centers for Disease Control and Prevention, Osong, South Korea.
Yeong-Min ParkDepartment of Immunology, Laboratory of Dendritic Cell Differentiation and Regulation, School of Medicine, Konkuk University, Chungju, South Korea.
Seung Hyun HanDepartment of Oral Microbiology and Immunology, DRI and BK21 Plus Program, School of Dentistry, Seoul National University, Seoul, South Korea.
Cheol-Heui YunDepartment of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, South Korea.
Seoul National University · KRInha University · KRInstitute for Basic Science · KRJeonbuk National University · KRKonkuk University · KRKorea Center for Disease Control and Prevention · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

γδ T cells, known to be an important source of innate IL-17 in mice, provide critical contributions to host immune responses. Development and function of γδ T cells are directed by networks of diverse transcription factors (TFs). Here, we examine the role of the zinc finger TFs, Kruppel-like factor 10 (KLF10), in the regulation of IL-17-committed CD27

Indexed as

Signal TransductionAnimalsBone Marrow CellsCD5 AntigensEarly Growth Response Transcription FactorsGene Expression RegulationHomeostasisInterleukin-17Interleukin-7 Receptor alpha SubunitKruppel-Like Transcription FactorsMiceMice, Inbred C57BLMice, KnockoutReceptors, Antigen, T-Cell, gamma-deltaT-LymphocytesTumor Necrosis Factor Receptor Superfamily, Member 7CD5 AntigensCd5 protein, mouseEarly Growth Response Transcription FactorsInterleukin-17Interleukin-7 Receptor alpha SubunitKLF10 protein, mouseKruppel-Like Transcription FactorsReceptors, Antigen, T-Cell, gamma-deltaTumor Necrosis Factor Receptor Superfamily, Member 7homeostasisIL-17Innate-like γδ-17KLF10γδ T cells

Identifiers

PMID29541070
PMCPMC5835516
OpenAlexW2793001825

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.