ArticleFrontiers in neuroscience2018
Galvanic Vestibular Stimulation (GVS) Augments Deficient Pedunculopontine Nucleus (PPN) Connectivity in Mild Parkinson's Disease: fMRI Effects of Different Stimuli.
Article in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Galvanic vestibular stimulation and its applications: a systematic review.Brazilian journal of otorhinolaryngologyPooled it
- Vestibular nucleus stimulation for ameliorating locomotor dynamics in a Parkinsonian mouse model.Nature communications · 2026Article
- Effects of galvanic vestibular stimulation on motor control in patients with Parkinson's disease: study protocol.Arquivos de neuro-psiquiatria · 2026Article
- A consistent vigor network in Parkinson's disease: a potential target for brain stimulation effects.Frontiers in human neuroscience · 2026Article
- Noisy galvanic vestibular stimulation and static balance in parkinson's disease: a multimodal resting‑state fMRI feasibility study.Journal of neuroengineering and rehabilitation · 2025Article
- Functional brain activity in persistent postural-perceptual dizziness (PPPD) during galvanic vestibular stimulation reveals sensitization in the multisensory vestibular cortical network.Scientific reports · 2025Article
- Galvanic vestibular stimulation to rehabilitate postural instability in Parkinson's disease.Arquivos de neuro-psiquiatria · 2025Article
- A review of parameter settings for galvanic vestibular stimulation in clinical applications.Frontiers in human neuroscience · 2025Review
- Article
- Vestibular Neurostimulation for Parkinson's Disease: A Novel Device-Aided Non-Invasive Therapeutic Option.Journal of personalized medicine · 2024Review
- Postural motion perception during vestibular stimulation depends on the motion perception threshold in persistent postural-perceptual dizziness.Journal of neurology · 2024Article
- No evidence for effects of low-intensity vestibular noise stimulation on mild-to-moderate gait impairments in patients with Parkinson's disease.Journal of neurology · 2024Article
- Disrupted Brain Network Measures in Parkinson's Disease Patients with Severe Hyposmia and Cognitively Normal Ability.Brain sciences · 2024Article
- Low-intensity vestibular noise stimulation improves postural symptoms in progressive supranuclear palsy.Journal of neurology · 2024Article
- Older adults and individuals with Parkinson's disease control posture along suborthogonal directions that deviate from the traditional anteroposterior and mediolateral directions.Scientific reports · 2024Article
- Vestibular dysfunction in Parkinson's disease: a neglected topic.Frontiers in neurology · 2024Review
- Vestibular Sensory Conflict During Postural Control, Freezing of Gait, and Falls in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2022Article
- Cholinergic system changes in Parkinson's disease: emerging therapeutic approaches.The Lancet. Neurology · 2022Review
- Why Should Constant Stimulation of Saccular Afferents Modify the Posture and Gait of Patients with Bilateral Vestibular Dysfunction? The Saccular Substitution Hypothesis.Journal of clinical medicine · 2022Review
- Walking exercise alters pedunculopontine nucleus connectivity in Parkinson's disease in a dose-dependent manner.Frontiers in neuroscience · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Falls and balance difficulties remain a major source of morbidity in Parkinson's Disease (PD) and are stubbornly resistant to therapeutic interventions. The mechanisms of gait impairment in PD are incompletely understood but may involve changes in the Pedunculopontine Nucleus (PPN) and its associated connections. We utilized fMRI to explore the modulation of PPN connectivity by Galvanic Vestibular Stimulation (GVS) in healthy controls (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.