ArticleHypertension research : official journal of the Japanese Society of Hypertension2018
Prognostic significance of home pulse pressure for progression of diabetic nephropathy: KAMOGAWA-HBP study.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 6 citations in OpenAlex.
- Association of morning home systolic blood pressure and albuminuria with cardiovascular events in Japanese patients with type 2 diabetes mellitus: The KAMOGAWA-HBP study.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Hemodynamic phenotypes defined by arterial stiffness index and pulse pressure with risk of diabetic microvascular complications in type 2 diabetes.Frontiers in endocrinology · 2026Article
- Home blood pressure measurement: the original and the best for predicting the risk.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Home Blood Pressure Monitoring: Current Status and New Developments.American journal of hypertension · 2021Article
- Impact of Isolated High Home Systolic Blood Pressure and Diabetic Nephropathy in Patients with Type 2 Diabetes Mellitus: A 5-Year Prospective Cohort Study.Journal of clinical medicine · 2021Article
- Determinants of pulse pressure amplification in hypertensive and diabetic patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Diabetic nephropathy ameliorated in patients with normal home blood pressure compared to those with isolated high home systolic blood pressure: A 5-year prospective cohort study among patients with type 2 diabetes mellitus.Diabetes & vascular disease researchArticle
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10 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Pulse pressure (PP) has been noted as a potential independent risk factor for micro and macrovascular diabetic complications. We aimed to examine the prognostic value of home-measured PP (home PP) in patients with type 2 diabetes. This study is a 2-year prospective cohort study of 737 patients with type 2 diabetes. Home blood pressure measurements were performed for 14 consecutive days. We defined the progression of diabetic nephropathy as when the diabetic nephropathy stage advanced to a higher stage during the 2 years. Using logistic regression analyses, we investigated the relationship between home PP and home systolic blood pressure (SBP) in the morning and in the evening and the progression of diabetic nephropathy. Furthermore, we measured the area under the receiver-operating characteristic curve (AUC) to assess the predictive ability of the progression of diabetic nephropathy of home PP. During the 2-year study, progression of diabetic nephropathy was observed in 94 patients. The adjusted odds ratios (95% confidence interval (CI)) of home PP and home SBP to the progression of diabetic nephropathy were 1.23 (1.01-1.49) and 1.14 (0.98-1.33), respectively. The AUC (95% CI) of home PP to the progression of diabetic nephropathy was 0.624 (0.665-0.679). The optimal cut-off points, sensitivity and specificity for home PP that were associated with the progression of diabetic nephropathy were 57.7 mmHg, 0.649 and 0.580, respectively. Our findings suggest, for the first time, that home PP is an independent predictor of the progression of diabetic nephropathy in patients with type 2 diabetes.
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