ArticleNature communications2018
The preprophase band-associated kinesin-14 OsKCH2 is a processive minus-end-directed microtubule motor.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function.Cytoskeleton (Hoboken, N.J.) · 2026Review
- PalKCH1 and PalKCH2 are required for tension wood formation and gelatinous layer deposition inFrontiers in plant science · 2026Article
- Mutation of OsKIF14.3, a Kinesin-14 Subfamily Protein, Altered Starch Metabolism and Caused Yellowish Leaf in Rice.International journal of molecular sciences · 2025Article
- Plant Kinesin Repertoires Expand with New Domain Architecture and Contract with the Loss of Flagella.Journal of molecular evolution · 2024Article
- Calponin homology domain containing kinesin, KIS1, regulates chloroplast stromule formation and immunity.Science advances · 2023Article
- Microtubule Regulation in Plants: From Morphological Development to Stress Adaptation.Biomolecules · 2023Review
- Cytoplasmic dynein1 intermediate-chain2 regulates cellular trafficking and physiopathological development iniScience · 2023Article
- Abscisic acid induces the expression of AsKIN during the recovery period of garlic cryopreservation.Plant cell reports · 2022Article
- Comparative transcriptome and DNA methylation analysis in temperature-sensitive genic male sterile wheat BS366.BMC genomics · 2021Article
- A minus-end directed kinesin motor directs gravitropism in Physcomitrella patens.Nature communications · 2021Article
- The Tail of Kinesin-14a in Giardia Is a Dual Regulator of Motility.Current biology : CB · 2020Article
- Mislocalization of TORC1 to Lysosomes Caused by KIF11 Inhibition Leads to Aberrant TORC1 Activity.Molecules and cells · 2020Article
- A Tug-of-War Model Explains the Saltatory Sperm Cell Movement inFrontiers in plant science · 2020Article
- StructureMan: A Structure Manipulation Tool to Study Large Scale Biomolecular Interactions.Frontiers in molecular biosciences · 2020Article
- Maize VKS1 Regulates Mitosis and Cytokinesis During Early Endosperm Development.The Plant cell · 2019Article
- The Orphan Kinesin PAKRP2 Achieves Processive Motility via a Noncanonical Stepping Mechanism.Biophysical journal · 2019Article
- The KCH Kinesin Drives Nuclear Transport and Cytoskeletal Coalescence to Promote Tip Cell Growth inThe Plant cell · 2018Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In animals and fungi, cytoplasmic dynein is a processive minus-end-directed motor that plays dominant roles in various intracellular processes. In contrast, land plants lack cytoplasmic dynein but contain many minus-end-directed kinesin-14s. No plant kinesin-14 is known to produce processive motility as a homodimer. OsKCH2 is a plant-specific kinesin-14 with an N-terminal actin-binding domain and a central motor domain flanked by two predicted coiled-coils (CC1 and CC2). Here, we show that OsKCH2 specifically decorates preprophase band microtubules in vivo and transports actin filaments along microtubules in vitro. Importantly, OsKCH2 exhibits processive minus-end-directed motility on single microtubules as individual homodimers. We find that CC1, but not CC2, forms the coiled-coil to enable OsKCH2 dimerization. Instead, our results reveal that removing CC2 renders OsKCH2 a nonprocessive motor. Collectively, these results show that land plants have evolved unconventional kinesin-14 homodimers with inherent minus-end-directed processivity that may function to compensate for the loss of cytoplasmic dynein.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.