Evidence map›Paper›PMID 29540601›Full record

ArticleJournal of virology2018

Positive Regulation of Hepatitis E Virus Replication by MicroRNA-122.

Bangari Haldipur, Prudhvi Lal Bhukya, Vidya Arankalle, Kavita Lole

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Differential miRNA signatures in Hepatitis E Virus Infection: Insights into acute, chronic, and pregnancy-related outcomes.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Hepatitis E Virus Life Cycle.Advances in experimental medicine and biology · 2023
    Article
  13. Article
  14. Structural aspects of hepatitis E virus.Archives of virology · 2022
    Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Hepatitis E Virus Immunopathogenesis.Pathogens (Basel, Switzerland) · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bangari HaldipurHepatitis Division, National Institute of Virology, Microbial Containment Complex, Pune, India.
Prudhvi Lal BhukyaHepatitis Division, National Institute of Virology, Microbial Containment Complex, Pune, India.
Vidya ArankalleHepatitis Division, National Institute of Virology, Microbial Containment Complex, Pune, India.
Kavita LoleHepatitis Division, National Institute of Virology, Microbial Containment Complex, Pune, India lolekavita37@yahoo.com.
ICMR-National Institute of Virology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The molecular mechanisms of liver pathology and clinical disease in hepatitis E virus (HEV) infection remain unclear. MicroRNAs (miRNAs) are known to modulate viral pathogenesis either by directly altering viral gene expression or by enhancing cellular antiviral responses. Given the importance of microRNA-122 (miR-122) in liver pathobiology, we investigated possible role of miR-122 in HEV infection.

Indexed as

A549 CellsArgonaute ProteinsBase SequenceCell Line, TumorGenome, ViralHepatitis EHepatitis E virusHep G2 CellsHumansLiverMicroRNAsRNA-Dependent RNA PolymeraseVirus ReplicationAGO2 protein, humanArgonaute ProteinsMicroRNAsMIRN122 microRNA, humanRNA-Dependent RNA PolymeraseAgo2hepatitis E virusinteractionmiR-122target sitevirus replication

Identifiers

PMID29540601
PMCPMC5952168
OpenAlexW2794131033

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.