Evidence map›Paper›PMID 29540577›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

A High Throughput Whole Blood Assay for Analysis of Multiple Antigen-Specific T Cell Responses in Human

Wendy E Whatney, Neel R Gandhi, Cecilia S Lindestam Arlehamn, Azhar Nizam, Hao Wu, Melanie J Quezada, Angela Campbell, Salim Allana, Mbuyi Madeleine Kabongo, Jeremiah Khayumbi and 19 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Preservation of antigen-specific responses in cryopreserved CD4Journal of translational autoimmunity · 2022
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 4 institutions in 3 countries.

Wendy E WhatneyEmory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30329.
Neel R GandhiDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322.
Cecilia S Lindestam ArlehamnDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037.
Azhar NizamDepartment of Biostatistics, Rollins School of Public Health, Emory University, Atlanta, GA 30322.
Hao WuDepartment of Biostatistics, Rollins School of Public Health, Emory University, Atlanta, GA 30322.
Melanie J QuezadaEmory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30329.ORCID 0000-0002-2057-3477
Angela CampbellDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322.ORCID 0000-0003-3990-3656
Salim AllanaDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322.
Mbuyi Madeleine KabongoDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322.ORCID 0000-0002-5158-6860
Jeremiah KhayumbiCenter for Global Health Research, Kenya Medical Research Institute, Kisumu 40100, Kenya.
Benson MuchiriCenter for Global Health Research, Kenya Medical Research Institute, Kisumu 40100, Kenya.
Joshua OngaloCenter for Global Health Research, Kenya Medical Research Institute, Kisumu 40100, Kenya.ORCID 0000-0002-4968-6176
Joan TonuiCenter for Global Health Research, Kenya Medical Research Institute, Kisumu 40100, Kenya.
Loren E SasserEmory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30329.ORCID 0000-0003-3348-9933
Tawania J FergusDepartment of Medicine, New York University School of Medicine, New York, NY 10016.
Gregory Sadat OumaCenter for Global Health Research, Kenya Medical Research Institute, Kisumu 40100, Kenya.
Samuel Gurrion OumaCenter for Global Health Research, Kenya Medical Research Institute, Kisumu 40100, Kenya.
Allison A BeckDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322.
Mark J MulliganDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322.
Alawode OladeleDeKalb County Board of Health, Atlanta, GA 30030.
Deepak KaushalTulane National Primate Research Center, Covington, LA 70433.ORCID 0000-0003-3521-1257
Kevin P CainDivision of Global HIV and Tuberculosis, U.S. Centers for Disease Control and Prevention, Kisumu 40100, Kenya; and.
Lance WallerDepartment of Biostatistics, Rollins School of Public Health, Emory University, Atlanta, GA 30322.ORCID 0000-0001-5002-8886
Henry M BlumbergDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322.
John D AltmanEmory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30329.
Joel D ErnstDepartment of Medicine, New York University School of Medicine, New York, NY 10016.ORCID 0000-0001-9951-6207
Jyothi RengarajanEmory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30329; cday@emory.edu jrengar@emory.edu.ORCID 0000-0003-1241-4705
Cheryl L DayEmory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30329; cday@emory.edu jrengar@emory.edu.
TBRU-ASTRa Study Group
Emory University · USKenya Medical Research Institute · KELa Jolla Institute for Immunology · USTulane University · US

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Carlos del Rio · 2002 to 2026
$74.0M
Role of antigen-specific T cell responses in the control of TBU19AI111211 · NIAID · EMORY UNIVERSITY · PI BLUMBERG, HENRY M, ERNST, JOEL D. · 2014 to 2020
$20.1M
NK cell-mediated regulation of T cell immunity in TB/HIV co-infectionR01AI111948 · NIAID · EMORY UNIVERSITY · PI DAY, CHERYL LIANE · 2014 to 2018
$3.7M
NIAID NIH HHS P30 AI050409NIAID NIH HHS R01 AI111948NIAID NIH HHS U19 AI111211NIH HHS P51 OD011104NIH HHS P51 OD011132
6 · The paper itself

Abstract

Antigen-specific CD4 and CD8 T cells are important components of the immune response to

Indexed as

Cross-Sectional StudiesHematologic TestsHigh-Throughput Screening AssaysHumansImmunologic TechniquesLongitudinal StudiesReproducibility of ResultsT-LymphocytesTuberculosis

Identifiers

PMID29540577
PMCPMC5995335
OpenAlexW2791731552

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.