Evidence map›Paper›PMID 29540477›Full record

ArticleThe Journal of biological chemistry2018

The cellular stress proteins CHCHD10 and MNRR1 (CHCHD2): Partners in mitochondrial and nuclear function and dysfunction.

Neeraja Purandare, Mallika Somayajulu, Maik Hüttemann, Lawrence I Grossman, Siddhesh Aras

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 69 citations in OpenAlex.

  1. Frontotemporal dementia associated CHCHD10Cell death & disease · 2026
    Article
  2. Article
  3. MYEOV Is a Novel Marker of Differentiated Corneal Epithelium.Investigative ophthalmology & visual science · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Chchd10: A Novel Metabolic Sensor Modulating Adipose Tissue Homeostasis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  10. Signal integrator function of CXXC5 in Cancer.Cell communication and signaling : CCS · 2025
    Review
  11. Review
  12. Review
  13. Article
  14. Mitochondrial Factors in the Cell Nucleus.International journal of molecular sciences · 2023
    Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Neeraja PurandareFrom the Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48201.
Mallika SomayajuluFrom the Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48201.
Maik HüttemannFrom the Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48201.
Lawrence I GrossmanFrom the Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48201 lgrossman@wayne.edu.
Siddhesh ArasFrom the Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48201.
Wayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coiled-coil-helix-coiled-coil-helix domain-containing 10 (CHCHD10) and CHCHD2 (MNRR1) are homologous proteins with 58% sequence identity and belong to the twin CX

Indexed as

Response ElementsTranscription, GeneticCarrier ProteinsCell NucleusDNA-Binding ProteinsHEK293 CellsHeLa CellsHumansMitochondriaMitochondrial ProteinsOxygen ConsumptionProtein-Tyrosine KinasesProto-Oncogene MasReactive Oxygen SpeciesTranscription FactorsARG tyrosine kinaseCarrier ProteinsCHCHD10 protein, humanCHCHD2 protein, humanCXXC5 protein, humanDNA-Binding ProteinsMAS1 protein, humanMitochondrial ProteinsProtein-Tyrosine KinasesProto-Oncogene MasReactive Oxygen SpeciesTranscription Factorscell stresscytochrome c oxidase (Complex IV)energy metabolismhypoxiamitochondriamitochondrial diseaseneurodegenerative diseasescaffolding proteintranscriptional regulator

Identifiers

PMID29540477
PMCPMC5925800
OpenAlexW2790217549

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.