Evidence map›Paper›PMID 29540454›Full record

ArticleJournal of clinical microbiology2018

One Year in the Life of a Rapid Syndromic Panel for Meningitis/Encephalitis: a Pediatric Tertiary Care Facility's Experience.

Samia N Naccache, Maryann Lustestica, Margil Fahit, Javier Mestas, Jennifer Dien Bard

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Review
  5. Review
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Group B Streptococcal Neonatal Meningitis.Clinical microbiology reviews · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Unexpectedly High False-Positive Rates forFrontiers in cellular and infection microbiology · 2021
    Article
  15. Impact of cerebrospinal fluid syndromic testing in the management of children with suspected central nervous system infection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Article
  16. Panels and Syndromic Testing in Clinical Microbiology.Clinics in laboratory medicine · 2020
    Review
  17. Article
  18. Article
  19. Point-of-care multiplexed diagnosis of meningitis using the FilmArray® ME panel technology.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Samia N NaccacheDepartment of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA.
Maryann LustesticaDepartment of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA.
Margil FahitDepartment of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA.
Javier MestasDepartment of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA.
Jennifer Dien BardDepartment of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA jdienbard@chla.usc.edu.
Children's Hospital of Los Angeles · USUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early establishment of infectious processes allows for expedited clinical management of meningitis and encephalitis. The FilmArray meningitis/encephalitis (FA-M/E) panel provides rapid detection of potential pathogens associated with encephalitis/meningitis in both immunocompetent and compromised patients. Here, we conducted a 1-year review of the performance of the FA-M/E panel at a tertiary care children's hospital. Two hundred sixty-five samples from 251 patients were tested. We found 87.25% (219/251) were negative, 9.96% (25/251) were positive for viral analytes, and 3.19% (8/251) were positive for bacterial analytes. When possible, positive results were confirmed by alternate testing; 4/6 available bacterial positives and 17/20 available viral positives were confirmed by retrospective culture or molecular testing.

Indexed as

BacteriaCerebrospinal FluidChildEncephalitisHumansLos AngelesMeningitisMolecular Diagnostic TechniquesProgram EvaluationReagent Kits, DiagnosticReproducibility of ResultsRetrospective StudiesTertiary Health CareVirusesReagent Kits, DiagnosticencephalitisFilmArraymeningitispediatricsyndromic panel

Identifiers

PMID29540454
PMCPMC5925728
OpenAlexW2790750882

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.