ReviewNeuroscience and biobehavioral reviews2018
Rewiring the connectome: Evidence and effects.
Review in Neuroscience and biobehavioral reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- The Cerebellar Connectome.Cerebellum (London, England) · 2026Article
- Remembering the "when": Hebbian memory models for the time of past events.PLoS computational biology · 2026Article
- Remodeling synaptic connections via engineered neuron-astrocyte interactions.Nature communications · 2026Article
- Trans-synaptic modulation of cholinergic circuits tunes opioid reinforcement.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Review of the Brain's Behaviour after Injury and Disease for Its Application in an Agent-Based Model (ABM).Biomimetics (Basel, Switzerland) · 2024Review
- Parent attention-orienting behavior is associated with neural entropy in infancy.bioRxiv : the preprint server for biology · 2024Article
- An Agent-Based Model to Reproduce the Boolean Logic Behaviour of Neuronal Self-Organised Communities through Pulse Delay Modulation and Generation of Logic Gates.Biomimetics (Basel, Switzerland) · 2024Article
- Transient destabilization of interhemispheric functional connectivity induced by spreading depolarization.Network neuroscience (Cambridge, Mass.) · 2024Article
- Between neurons and networks: investigating mesoscale brain connectivity in neurological and psychiatric disorders.Frontiers in neuroscience · 2024Review
- Synchronization in STDP-driven memristive neural networks with time-varying topology.Journal of biological physics · 2023Article
- Experience-dependent effects of passive auditory exposure in infants impact theta phase synchrony and predict later language.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Diffusion tensor imaging discriminates focal cortical dysplasia from normal brain parenchyma and differentiates between focal cortical dysplasia types.Insights into imaging · 2023Article
- Circuit formation in the adult brain.The European journal of neuroscience · 2022Review
- The impact of neuron morphology on cortical network architecture.Cell reports · 2022Article
- Structure and function differences in the prelimbic cortex to basolateral amygdala circuit mediate trait vulnerability in a novel model of acute social defeat stress in male mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Article
- Tuning brain networks: The emerging role of transcranial direct current stimulation on structural plasticity.Frontiers in cellular neuroscience · 2022Review
- FARCI: Fast and Robust Connectome Inference.Brain sciences · 2021Article
- Nested information processing in the living world.Annals of the New York Academy of Sciences · 2021Review
- The role of nuclear Ca2+ in maintaining neuronal homeostasis and brain health.Journal of cell science · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Neuronal connections form the physical basis for communication in the brain. Recently, there has been much interest in mapping the "connectome" to understand how brain structure gives rise to brain function, and ultimately, to behaviour. These attempts to map the connectome have largely assumed that connections are stable once formed. Recent studies, however, indicate that connections in mammalian brains may undergo rewiring during learning and experience-dependent plasticity. This suggests that the connectome is more dynamic than previously thought. To what extent can neural circuitry be rewired in the healthy adult brain? The connectome has been subdivided into multiple levels of scale, from synapses and microcircuits through to long-range tracts. Here, we examine the evidence for rewiring at each level. We then consider the role played by rewiring during learning. We conclude that harnessing rewiring offers new avenues to treat brain diseases.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.