Evidence map›Paper›PMID 29540231›Full record

ReviewItalian journal of pediatrics2018

Vitamin K deficiency: a case report and review of current guidelines.

Maria Rosaria Marchili, Elisa Santoro, Alessandra Marchesi, Simona Bianchi, Lelia Rotondi Aufiero, Alberto Villani

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Italian journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
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  9. Article
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  13. Management of rare acquired bleeding disorders.Hematology. American Society of Hematology. Education Program · 2019
    Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Maria Rosaria MarchiliPediatric and Infectious Disease Unit, Bambino Gesu' Children's Hospital, IRCCS, Piazza Sant'Onofrio 4, Rome, Italy. mrosaria.marchili@opbg.net.
Elisa SantoroPediatric Department, University of Tor Vergata, Rome, Italy.
Alessandra MarchesiPediatric and Infectious Disease Unit, Bambino Gesu' Children's Hospital, IRCCS, Piazza Sant'Onofrio 4, Rome, Italy.
Simona BianchiPediatric and Infectious Disease Unit, Bambino Gesu' Children's Hospital, IRCCS, Piazza Sant'Onofrio 4, Rome, Italy.
Lelia Rotondi AufieroPediatric and Infectious Disease Unit, Bambino Gesu' Children's Hospital, IRCCS, Piazza Sant'Onofrio 4, Rome, Italy.
Alberto VillaniPediatric and Infectious Disease Unit, Bambino Gesu' Children's Hospital, IRCCS, Piazza Sant'Onofrio 4, Rome, Italy.
Bambino Gesù Children's Hospital · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamin K, a fat soluble vitamin, is a necessary cofactor for the activation of coagulation factors II, VII, IX, X, and protein C and S. In neonatal period, vitamin K deficiency may lead to Vitamin K Deficiency Bleeding (VKDB). CASE PRESENTATION: We present the case of a 2 months and 20 days Caucasian male, presented for bleeding from the injections sites of vaccines. At birth oral vitamin K prophylaxis was administered. Neonatal period was normal. He was exclusively breastfed and received a daily oral supplementation with 25 μg of vitamin K. A late onset vitamin K deficiency bleeding was suspected. Intravenous Vitamin K was administered with complete recovery.

conclusionsNevertheless the oral prophylaxis, our case developed a VKDB: it is necessary to revise the current guidelines in order to standardize timing and dosage in different clinical conditions.

Indexed as

Practice Guidelines as TopicAdministration, OralAntifibrinolytic AgentsHemorrhageHumansInfantMaleVitamin KVitamin K DeficiencyAntifibrinolytic AgentsVitamin KBleedingBreastfeedingCase reportDeficiencyVitamin K

Identifiers

PMID29540231
PMCPMC5853086
OpenAlexW2799978148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.