Evidence map›Paper›PMID 29540181›Full record

Trial reportPediatric rheumatology online journal2018

Improvement of medication adherence in adolescents and young adults with SLE using web-based education with and without a social media intervention, a pilot study.

Lisabeth V Scalzi, Christopher S Hollenbeak, Emily Mascuilli, Nancy Olsen

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Pediatric rheumatology online journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03218033 (Improvement of Medication Adherence in Adolescents With SLE Using Web-based Education With and Without a Social Media Intervention), which is not on this map. Cited by 37 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03218033 nacompletednot on this map

Improvement of Medication Adherence in Adolescents With SLE Using Web-based Education With and Without a Social Media Intervention

TypeinterventionalSponsorMilton S. Hershey Medical CenterRan2014 to 2015Enrolled37ConditionsSystemic LupusArmsSocial Media
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Trial
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Lisabeth V ScalziPennsylvania State University, MC A480; 90 Hope Drive, Hershey, PA, 17033, USA. lscalzi@pennstatehealth.psu.edu.ORCID http://orcid.org/0000-0003-0374-4841
Christopher S HollenbeakPennsylvania State University, MC A480; 90 Hope Drive, Hershey, PA, 17033, USA.
Emily MascuilliPennsylvania State University, MC A480; 90 Hope Drive, Hershey, PA, 17033, USA.
Nancy OlsenPennsylvania State University, MC A480; 90 Hope Drive, Hershey, PA, 17033, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSelf-management skills, including medication management, are vital to the health of adolescents and young adults with systemic lupus erythematosus (SLE). The purpose of this study was to assess the feasibility and preliminary effects of an online educational program in a cohort of adolescent and young adults with SLE with and without a social media (SM) experience.

methodsAdolescents and young adults with SLE participated weekly for 8 sessions on a web-based educational program about SLE created specifically for this project. Subjects were randomized to respond to questions at the end of each weekly module in a journal or on a SM forum with other SLE subjects. Patients were surveyed prior to initiating the study, (T0) and 6 weeks after completion of the sessions (T1). Medication adherence for hydroxychloroquine, utilizing the medication possession ratio (MPR), was compared for the 3 months preceding T0 and for the 3 months following T1.

resultsTwenty-seven of the 37 subjects (73%) enrolled completed the study, including the two required sets of surveys. Reasons for being lost to follow up included being too busy, forgetting, and/or not seeing email reminders. Medication adherence improved in all subjects (p < 0.001). The percentage of the SM intervention group that was adherent (MPR ≥ 80%) significantly improved from 50% to 92% (p = 0.03), while the control group did not. Secondary outcome measures that improved, only in the SM group, included self-efficacy, sense of agency (SOA), sense of community (SOC), and empowerment. There was a strong correlation between empowerment with SOA and SOC and in turn a strong correlation with SOA and SOC with MPR, providing a possible explanation for why social media participation helped to improve medication adherence. Subjective reporting of medication adherence was not reliably correlated to MPR.

conclusionsThis pilot study has demonstrated feasibility for the use of an online educational SLE website, recruitment, and measurement of chosen outcome measures. This study provides evidence for a larger multi-site trial which has the potential to address an important service gap by delivering self-management education and peer interactions in a format that is accessible, and engaging to young people with SLE.

trial registrationTrial registration: NCT03218033 . Retrospectively registered 14 July 2017.

Indexed as

Drug MonitoringAdolescentAntirheumatic AgentsEducation, DistanceFeasibility StudiesFemaleHumansHydroxychloroquineInternetLupus Erythematosus, SystemicMalePatient Education as TopicPilot ProjectsProgram EvaluationRetrospective StudiesSelf EfficacyAntirheumatic AgentsHydroxychloroquineFeasibilityMedication adherenceSelf-managementSocial mediaSystemic lupus erythematosus

Identifiers

PMID29540181
PMCPMC5852975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.