Evidence map›Paper›PMID 29538456›Full record

ArticlePloS one2018

A trauma network with centralized and local health care structures: Evaluating the effectiveness of the first certified Trauma Network of the German Society of Trauma Surgery.

Antonio Ernstberger, Michael Koller, Florian Zeman, Maximilian Kerschbaum, Franz Hilber, Eva Diepold, Julika Loss, Tanja Herbst, Michael Nerlich, Trauma Centers of the Trauma Network of Eastern Bavaria (TraumaNetzwerk Ostbayern − TNO)

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Transport and destination hospital for patients with suspected multiple and/or severe injuries - a systematic review and clinical practice guideline update.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Pooled it
  2. Guideline
  3. Article
  4. Independence of the mortality of severely injured patients from types of transport and hospital level in a well-developed trauma network.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Article
  5. Article
  6. It is (not) always on Friday: inter-hospital patient transfers in orthopedic and trauma surgery.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
    Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Quality of life after multiple trauma: results from a patient cohort treated in a certified trauma network.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Antonio ErnstbergerDepartment of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany.ORCID 0000-0001-6518-147X
Michael KollerCenter for Clinical Studies, University Medical Center Regensburg, Regensburg, Germany.
Florian ZemanCenter for Clinical Studies, University Medical Center Regensburg, Regensburg, Germany.
Maximilian KerschbaumDepartment of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany.
Franz HilberDepartment of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany.
Eva DiepoldDepartment of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany.
Julika LossInstitute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.
Tanja HerbstDepartment of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany.
Michael NerlichDepartment of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany.
Trauma Centers of the Trauma Network of Eastern Bavaria (TraumaNetzwerk Ostbayern − TNO)
University Hospital Regensburg · DEUniversity of Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTrauma is a global burden of disease and one of the main causes of death worldwide. Therefore, many countries around the world have implemented a wide range of different initiatives to minimize mortality rates after trauma. One of these initiatives is the bundling of treatment expertise in trauma centers and the establishment of trauma networks. Germany has a decentralized system of trauma care medical centers. Severely injured patients ought to receive adequate treatment in both level I and level II centers. This study investigated the effectiveness of a decentralized network and the question whether level I and level II centers have comparable patient outcome. MATERIALS AND

methodsIn 2009, the first trauma network DGU® in Germany was certified in the rural area of Eastern Bavaria. All patients admitted to the 25 participating hospitals were prospectively included in this network in the framework of a study sponsored by the German Federal Ministry of Education and Research between March 2012 and February 2014. 2 hospitals were level I centers (maximal care centers), 8 hospitals were level II centers, and 15 hospitals were level III centers. The criterion for study inclusion was an injury severity score (ISS) ≥ 16 for patients´ primarily admitted to a level I or a level II center. Exclusion criteria were transferal to another hospital within 48 h, an unknown revised injury severity classification II score (RISC II), or primary admittance to a level III center (n = 52). 875 patients were included in the study. Univariate analyses were used regarding the preclinical and clinical parameters, the primary endpoint mortality rate, and the secondary endpoints length of stay, organ failure, and neurological outcome (GOS). The primary endpoint was additionally evaluated by means of multivariable analysis.

resultsIndices for injury severity (GCS, AISHead, ISS, and NISS) as well as the predicted probability of death (RISC II) were higher in level I centers than in level II centers. No significant differences were found between the mortality rate of the unadjusted analysis [level I: 21.6% (CI: 16.5, 27.9), level II: 18.1% (CI: 14.4, 22.5), p = 0.28] and that of the adjusted analysis [level I SMR: 0.94 (CI: 0.72, 1.21), level II SMR: 1.18 (CI 0.95, 1.48) SMR: expected vs. calculated mortality rate according to RISC II]. Multivariable analysis showed a survival advantage of patients admitted to a level I center with a probability of death of 13% (RISC II). The number need to treat was 10 patients. DISCUSSION: This study showed that a rural trauma network with centralized and local structures may achieve equivalent results with regard to mortality rates to those obtained in level I and level II centers. These results were furthered by a certain preclinical centralization (24/7 air rescue) of patients. The study also showed a survival advantage of patients admitted to a level I center with a probability of death of 13%. Preclinical and initial clinical evaluation with regard to probable mortality rates should be further improved to identify patients who would benefit from admittance to a level I center.

Indexed as

Health FacilitiesHealth ServicesAdultAgedEmergency Medical ServicesFemaleGermanyHumansMaleMiddle AgedOdds RatioOutcome Assessment, Health CareProspective StudiesQuality ImprovementROC CurveTrauma Centers

Identifiers

PMID29538456
PMCPMC5851627
OpenAlexW2793902662

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.