Evidence map›Paper›PMID 29538439›Full record

ArticlePloS one2018

Maternal DNA lineages at the gate of Europe in the 10th century AD.

Ioana Rusu, Alessandra Modi, Stefania Vai, Elena Pilli, Cristina Mircea, Claudia Radu, Claudia Urduzia, Zeno Karl Pinter, Vitalie Bodolică, Cătălin Dobrinescu and 5 more

Abstract readHistorical Article
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. A genetic perspective on Longobard-Era migrations.European journal of human genetics : EJHG · 2019
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ioana RusuMolecular Biology Center, Interdisciplinary Research Institute on Bio-Nano-Sciences, Babeș-Bolyai University, Cluj-Napoca, Romania.ORCID 0000-0002-6152-8832
Alessandra ModiDipartimento di Biologia, Università di Firenze, Florence, Italy.
Stefania VaiDipartimento di Biologia, Università di Firenze, Florence, Italy.
Elena PilliDipartimento di Biologia, Università di Firenze, Florence, Italy.
Cristina MirceaMolecular Biology Center, Interdisciplinary Research Institute on Bio-Nano-Sciences, Babeș-Bolyai University, Cluj-Napoca, Romania.
Claudia RaduMolecular Biology Center, Interdisciplinary Research Institute on Bio-Nano-Sciences, Babeș-Bolyai University, Cluj-Napoca, Romania.
Claudia UrduziaBrukenthal National Museum, Sibiu, Romania.
Zeno Karl PinterDepartment of History, Heritage and Protestant Theology, Lucian Blaga University of Sibiu, Sibiu, Romania.
Vitalie BodolicăDepartment of Research-Development and Projects, Museum of National History and Archeology, Constanța, Romania.
Cătălin DobrinescuDepartment of Research-Development and Projects, Museum of National History and Archeology, Constanța, Romania.
Montserrat HervellaDepartment of Genetics, Physical Anthropology and Animal Physiology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Bizkaia, Spain.
Octavian PopescuMolecular Biology Center, Interdisciplinary Research Institute on Bio-Nano-Sciences, Babeș-Bolyai University, Cluj-Napoca, Romania.
Martina LariDipartimento di Biologia, Università di Firenze, Florence, Italy.
David CaramelliDipartimento di Biologia, Università di Firenze, Florence, Italy.
Beatrice KelemenMolecular Biology Center, Interdisciplinary Research Institute on Bio-Nano-Sciences, Babeș-Bolyai University, Cluj-Napoca, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the paucity of archaeogenetic data available for medieval European populations in comparison to other historical periods, the genetic landscape of this age appears as a puzzle of dispersed, small, known pieces. In particular, Southeastern Europe has been scarcely investigated to date. In this paper, we report the study of mitochondrial DNA in 10th century AD human samples from Capidava necropolis, located in Dobruja (Southeastern Romania, Southeastern Europe). This geographical region is particularly interesting because of the extensive population flux following diverse migration routes, and the complex interactions between distinct population groups during the medieval period. We successfully amplified and typed the mitochondrial control region of 10 individuals. For five of them, we also reconstructed the complete mitochondrial genomes using hybridization-based DNA capture combined with Next Generation Sequencing. We have portrayed the genetic structure of the Capidava medieval population, represented by 10 individuals displaying 8 haplotypes (U5a1c2a, V1a, R0a2'3, H1, U3a, N9a9, H5e1a1, and H13a1a3). Remarkable for this site is the presence of both Central Asiatic (N9a) and common European mtDNA haplotypes, establishing Capidava as a point of convergence between East and West. The distribution of mtDNA lineages in the necropolis highlighted the existence of two groups of two individuals with close maternal relationships as they share the same haplotypes. We also sketch, using comparative statistical and population genetic analyses, the genetic relationships between the investigated dataset and other medieval and modern Eurasian populations.

Indexed as

ArchaeologyBone and BonesDNA, MitochondrialGenetics, PopulationHaplotypesHigh-Throughput Nucleotide SequencingHistory, MedievalHumansPhylogenyPrincipal Component AnalysisRomaniaSequence Analysis, DNAWhite PeopleDNA, Mitochondrial

Identifiers

PMID29538439
PMCPMC5851556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.