Evidence map›Paper›PMID 29538357›Full record

ArticlePediatric research2018

Pulmonary and diaphragmatic pathology in collagen type I α1 mutant mice with osteogenesis imperfecta.

Carolyn J Baglole, Feng Liang, Hussein Traboulsi, Angela Rico de Souza, Christian Giordano, Josephine T Tauer, Frank Rauch, Basil J Petrof

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Pediatric research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. A new Col1a1 conditional knock-in mouse model to study osteogenesis imperfecta.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
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  18. Aryl hydrocarbon receptor deficiency causes the development of chronic obstructive pulmonary disease through the integration of multiple pathogenic mechanisms.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Carolyn J BagloleMeakins-Christie Laboratories and Respiratory Division, McGill University, Montreal, Quebec, Canada.
Feng LiangMeakins-Christie Laboratories and Respiratory Division, McGill University, Montreal, Quebec, Canada.
Hussein TraboulsiMeakins-Christie Laboratories and Respiratory Division, McGill University, Montreal, Quebec, Canada.
Angela Rico de SouzaMeakins-Christie Laboratories and Respiratory Division, McGill University, Montreal, Quebec, Canada.
Christian GiordanoMeakins-Christie Laboratories and Respiratory Division, McGill University, Montreal, Quebec, Canada.
Josephine T TauerShriners Hospital for Children and McGill University, Montreal, Quebec, Canada.
Frank RauchShriners Hospital for Children and McGill University, Montreal, Quebec, Canada.
Basil J PetrofMeakins-Christie Laboratories and Respiratory Division, McGill University, Montreal, Quebec, Canada.
Christie (Canada) · CAMcGill University · CAMontreal Children's Hospital · CA

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

BackgroundOsteogenesis imperfecta (OI) is most often caused by mutations in type I collagen genes. Respiratory complications have been largely attributed to spine and ribcage deformities. We hypothesized that direct involvement of the pulmonary parenchyma and/or diaphragm by the disease may occur.MethodsIn Col1a1

Indexed as

AnimalsAntibodies, NeutralizingBone and BonesCollagen Type ICollagen Type I, alpha 1 ChainDiaphragmDisease Models, AnimalFemaleLungMaleMiceMice, Mutant StrainsMuscle ContractionMyosin Heavy ChainsOsteogenesis ImperfectaPhenotypeAntibodies, NeutralizingCollagen Type ICollagen Type I, alpha 1 ChainMyosin Heavy ChainsTgfb1 protein, mouseTransforming Growth Factor beta1

Identifiers

PMID29538357
OpenAlexW2789760165

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.