Evidence map›Paper›PMID 29538306›Full record

ArticleMarine drugs2018

Anti-BACE1 and Antimicrobial Activities of Steroidal Compounds Isolated from Marine Urechis unicinctus.

Yong-Zhe Zhu, Jing-Wen Liu, Xue Wang, In-Hong Jeong, Young-Joon Ahn, Chuan-Jie Zhang

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 37 citations in OpenAlex.

  1. Bioactive compounds from fermentedIn silico pharmacology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Yong-Zhe ZhuCollege of Chemistry and Pharmaceutical Science, Qingdao Agricultural University, Changcheng Rd, Chengyang district, Qingdao 266109, China. zhuyzh2008@163.com.
Jing-Wen LiuCollege of Chemistry and Pharmaceutical Science, Qingdao Agricultural University, Changcheng Rd, Chengyang district, Qingdao 266109, China. mail.liujingwen@gmail.com.
Xue WangSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China. xinyuw001@163.com.
In-Hong JeongDivision of Crop Protection, National Institute of Agricultural Science, Rural Development Administration, Jeollabuk-do 55365, Korea. Inhongjeong@korea.kr.
Young-Joon AhnDepartment of Agricultural Biotechnology, Seoul National University, 599 Gwanak-ro, Silim-dong, Gwanak-Gu, Seoul 151742, Korea. yjahn@snu.ac.kr.
Chuan-Jie ZhangDepartment of Plant Science, University of Connecticut, 1376 Storrs Road, U-4163, Storrs, CT 06269, USA. chuanjiezhang@snu.ac.kr.ORCID 0000-0002-4430-3113
Qingdao Agricultural University · CNRural Development Administration · KRSeoul National University · KRUniversity of Connecticut · USWenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human β-site amyloid cleaving enzyme (BACE1) has been considered as an effective drug target for treatment of Alzheimer's disease (AD). In this study,

Indexed as

Alzheimer DiseaseAmyloid Precursor Protein SecretasesAnimalsAnti-Infective AgentsAquatic OrganismsAspartic Acid EndopeptidasesBacteriaBiological ProductsHumansPolychaetaSteroidsAmyloid Precursor Protein SecretasesAnti-Infective AgentsAspartic Acid EndopeptidasesBACE1 protein, humanBiological ProductsSteroidsAlzheimer’s diseaseantimicrobial activityBACE1bioassay-directed isolationmarine bioactiveUrechis unicinctus

Identifiers

PMID29538306
PMCPMC5867638
OpenAlexW2794192262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.