ArticleThe journal of spinal cord medicine2019
Epidural stimulation with locomotor training improves body composition in individuals with cervical or upper thoracic motor complete spinal cord injury: A series of case studies.
Article in The journal of spinal cord medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 47 citations in OpenAlex.
- Effect of hybrid FES exercise on body composition during the sub-acute phase of spinal cord injury.PloS one · 2022Trial
- Electrophysiological Guidance of Epidural Electrode Array Implantation over the Human Lumbosacral Spinal Cord to Enable Motor Function after Chronic Paralysis.Journal of neurotrauma · 2019Trial
- Central Serotonin Deficiency Impairs Recovery of Sensorimotor Abilities After Spinal Cord Injury in Rats.International journal of molecular sciences · 2025Article
- Epidural Stimulation and Resistance Training (REST-SCI) for Overground Locomotion After Spinal Cord Injury: Randomized Clinical Trial Protocol.Journal of clinical medicine · 2025Article
- The Potential of Spinal Cord Stimulation in Treating Spinal Cord Injury.Current pain and headache reports · 2025Review
- Synergistic implications of combinatorial rehabilitation approaches using spinal stimulation on therapeutic outcomes in spinal cord injury.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024Review
- Epidural Spinal Cord Stimulation for Spinal Cord Injury in Humans: A Systematic Review.Journal of clinical medicine · 2024Review
- DBS in the restoration of motor functional recovery following spinal cord injury.Frontiers in neurology · 2024Review
- Electrical stimulation of the cuneiform nucleus enhances the effects of rehabilitative training on locomotor recovery after incomplete spinal cord injury.Frontiers in neuroscience · 2024Article
- Spinal cord stimulation for spinal cord injury - Where do we stand? A narrative review.Journal of clinical orthopaedics and trauma · 2023Article
- Plasma Cytokines Level and Spinal Cord MRI Predict Clinical Outcome in a Rat Glial Scar Cryoinjury Model.Biomedicines · 2022Article
- A Review of Functional Restoration From Spinal Cord Stimulation in Patients With Spinal Cord Injury.Neurospine · 2022Article
- Impact of long-term epidural electrical stimulation enabled task-specific training on secondary conditions of chronic paraplegia in two humans.The journal of spinal cord medicine · 2021Article
- Electrical epidural stimulation of the cervical spinal cord: implications for spinal respiratory neuroplasticity after spinal cord injury.Journal of neurophysiology · 2021Review
- Serving the diverse community of spinal cord injury professionals: Topics and trends in research and care.The journal of spinal cord medicine · 2021Article
- A Western diet impairs CNS energy homeostasis and recovery after spinal cord injury: Link to astrocyte metabolism.Neurobiology of disease · 2020Article
- Multi-target approaches to CNS repair: olfactory mucosa-derived cells and heparan sulfates.Nature reviews. Neurology · 2020Review
- The feasibility of using exoskeletal-assisted walking with epidural stimulation: a case report study.Annals of clinical and translational neurology · 2020Article
- Epidural Electrical Stimulation: A Review of Plasticity Mechanisms That Are Hypothesized to Underlie Enhanced Recovery From Spinal Cord Injury With Stimulation.Frontiers in molecular neuroscience · 2020Article
- A Review of Different Stimulation Methods for Functional Reconstruction and Comparison of Respiratory Function after Cervical Spinal Cord Injury.Applied bionics and biomechanics · 2020Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
contextFour individuals with motor complete SCI with an implanted epidural stimulator who were enrolled in another study were assessed for cardiovascular fitness, metabolic function and body composition at four time points before, during, and after task specific training. Following 80 locomotor training sessions, a 16-electrode array was surgically placed on the dura (L1-S1 cord segments) to allow for electrical stimulation. After implantation individuals received 160 sessions of task specific training with epidural stimulation (stand and step). OUTCOME MEASURES: Dual-energy X-ray absorptiometry (DXA), resting metabolic rate and peak oxygen consumption (VO
findingsParticipants showed increases in lean body mass with decreases on percentage of body fat, particularly android body fat, and android/gynoid ratio from baseline to post training; resting metabolic rate and VO
conclusionsTask specific training combined with epidural stimulation has the potential to show improvements in cardiovascular fitness and body composition in individuals with cervical or upper thoracic motor complete SCI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.