Evidence map›Paper›PMID 29537838›Full record

ArticleJournal of the American Chemical Society2018

Characterization of Leader Peptide Binding During Catalysis by the Nisin Dehydratase NisB.

Lindsay M Repka, Kenton J Hetrick, See Hyun Chee, Wilfred A van der Donk

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Promiscuity of lanthipeptide enzymes: new challenges and applications.World journal of microbiology & biotechnology · 2025
    Review
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  11. Characterization of glutamyl-tRNA-dependent dehydratases using nonreactive substrate mimics.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lindsay M RepkaDepartment of Chemistry and Howard Hughes Medical Institute, University of Illinois, Urbana-Champaign , 600 South Mathews Avenue , Urbana , Illinois 61801 , United States.
Kenton J HetrickDepartment of Chemistry and Howard Hughes Medical Institute, University of Illinois, Urbana-Champaign , 600 South Mathews Avenue , Urbana , Illinois 61801 , United States.
See Hyun CheeDepartment of Chemistry and Howard Hughes Medical Institute, University of Illinois, Urbana-Champaign , 600 South Mathews Avenue , Urbana , Illinois 61801 , United States.
Wilfred A van der DonkDepartment of Chemistry and Howard Hughes Medical Institute, University of Illinois, Urbana-Champaign , 600 South Mathews Avenue , Urbana , Illinois 61801 , United States.ORCID 0000-0002-5467-7071
Howard Hughes Medical Institute · US

Funding

Posttranslational Modifications in Natural Product BiosynthesisR01GM058822 · NIGMS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI VAN DER DONK, WILFRED A. · 1999 to 2015
$3.8M
Posttranslational Modifications during Natural Product BiosynthesisR37GM058822 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI VAN DER DONK, WILFRED A. · 2016 to 2025
$2.9M
4800 Plus MALDI TOF/TOF AnalyzerS10RR027109 · NCRR · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI VAN DER DONK, WILFRED A. · 2010 to 2010
$395k
Mechanistic Understanding and Target Identification for Ribosomally Synthesized aF32GM108275 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI REPKA, LINDSAY MICHELLE · 2014 to 2015
$106k
Development and Utility of Phage Display of LanthipeptidesF31GM113486 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI HETRICK, KENTON · 2016 to 2017
$88k
NCRR NIH HHS S10 RR027109NIGMS NIH HHS F31 GM113486NIGMS NIH HHS F32 GM108275NIGMS NIH HHS R01 GM058822NIGMS NIH HHS R37 GM058822
6 · The paper itself

Abstract

The dehydratase NisB performs stepwise tRNA

Indexed as

Bacterial ProteinsBinding SitesBiocatalysisMembrane ProteinsPeptidesBacterial ProteinsMembrane ProteinsNisB protein, Lactococcus lactisPeptides

Identifiers

PMID29537838
PMCPMC5901694
OpenAlexW2790272132

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.