ArticleHealth promotion and chronic disease prevention in Canada : research, policy and practice2018
Childhood cancer incidence in Canada: demographic and geographic variation of temporal trends (1992-2010).
Article in Health promotion and chronic disease prevention in Canada : research, policy and practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 50 citations in OpenAlex.
- Pediatric Oncology Knowledge Mobilization in Canada: Protocol for an Environmental Scan.JMIR research protocols · 2026Article
- Temporal clustering of neuroblastic tumours in children and young adults from Scotland.Environmental health : a global access science source · 2026Article
- Anticancer activity of sulforaphane against human hepatoblastoma cells involves apoptosis, autophagy and inhibition of β-catenin signaling pathway.Archives of medical science : AMS · 2025Article
- Construction and validation of nomogram prognostic model for predicting survival in hepatoblastoma patients: a population-based study.Updates in surgery · 2024Article
- Epidemiology of Pediatric Tumors in Quebec: A 17-Year Report of Cancer in Young People in the Canada Registry.Current oncology (Toronto, Ont.) · 2024Article
- Relative risk of childhood and adolescence cancer in Iran: spatiotemporal analysis from 1999 to 2016.BMC research notes · 2024Article
- CanCHD Study of Hematopoietic Cancers in Children With and Without Genetic Syndromes.Journal of the American Heart Association · 2024Article
- Article
- Trends in childhood leukemia incidence in urban countries and their relation to environmental factors, including space weather.Frontiers in public health · 2024Article
- Unveiling perspectives on the psychosocial impacts of childhood cancer survival on young adult survivors' reassimilation journey: A qualitative exploration.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2024Article
- Counts, incidence rates, and trends of pediatric cancer in the United States, 2003-2019.Journal of the National Cancer Institute · 2023Article
- Case report: Catecholamine cardiomyopathy in children with neuroblastoma.Frontiers in pediatrics · 2023Article
- Parents' Experiences with Home-Based Oral Chemotherapy Prescribed to a Child Diagnosed with Acute Lymphoblastic Leukemia: A Qualitative Study.Current oncology (Toronto, Ont.) · 2021Article
- Incidence of Childhood Leukemia in Iraq, 2000-2019.Asian Pacific journal of cancer prevention : APJCP · 2021Article
- Neuroblastoma Among Omani Children: Clinical characteristics and survival outcome from a dedicated centre.Sultan Qaboos University medical journal · 2021Article
- Patterns and trends of cancer incidence in children and adolescents in China, 2011-2015: A population-based cancer registry study.Cancer medicine · 2021Article
- Canadian Consensus for Biomarker Testing and Treatment of TRK Fusion Cancer in Pediatric Patients.Current oncology (Toronto, Ont.) · 2021Article
- Flow cytometry of bone marrow aspirates from neuroblastoma patients is a highly sensitive technique for quantification of low-level neuroblastoma.F1000Research · 2021Article
- Comparison of Incidence and Outcomes of Neuroblastoma in Children, Adolescents, and Adults in the United States: A Surveillance, Epidemiology, and End Results (SEER) Program Population Study.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- The incidence of childhood cancer in Australia, 1983-2015, and projections to 2035.The Medical journal of Australia · 2020Article
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3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSurveillance of childhood cancer incidence trends can inform etiologic research, policy and programs. This study presents the first population-based report on demographic and geographic variations in incidence trends of detailed pediatric diagnostic groups in Canada.
methodsThe Canadian Cancer Registry data were used to calculate annual age-standardized incidence rates (ASIRs) from 1992 to 2010 among children less than 15 years of age by sex, age and region for the 12 main diagnostic groups and selected subgroups of the International Classification of Childhood Cancer (ICCC), 3rd edition. Temporal trends were examined by annual percent changes (APCs) using Joinpoint regression.
resultsThe ASIRs of childhood cancer among males increased by 0.5% (95% confidence interval (CI) = 0.2-0.9) annually from 1992 to 2010, whereas incidence among females increased by 3.2% (CI = 0.4-6.2) annually since 2004 after an initial stabilization. The largest overall increase was observed in children aged 1-4 years (APC = 0.9%, CI = 0.4-1.3). By region, the overall rates increased the most in Ontario from 2006 to 2010 (APC = 5.9%, CI = 1.9-10.1), and increased non-significantly in the other regions from 1992 to 2010. Average annual ASIRs for all cancers combined from 2006 to 2010 were lower in the Prairies (149.4 per million) and higher in Ontario (170.1 per million). The ASIRs increased for leukemias, melanoma, carcinoma, thyroid cancer, ependymomas and hepatoblastoma for all ages, and neuroblastoma in 1-4 year olds. Astrocytoma decreased in 10-14 year olds (APC = -2.1%, CI = -3.7 to -0.5), and among males (APC = -2.4%, CI = -4.6 to -0.2) and females (APC = -3.7%, CI = -5.8 to -1.6) in Ontario over the study period.
conclusionIncreasing incidence trends for all cancers and selected malignancies are consistent with those reported in other developed countries, and may reflect the changes in demographics and etiological exposures, and artefacts of changes in cancer coding, diagnosis and reporting. Significant decreasing trend for astrocytoma in late childhood was observed for the first time.
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