Evidence map›Paper›PMID 29537385›Full record

ArticlePhysics in medicine and biology2018

Low dose CBCT reconstruction via prior contour based total variation (PCTV) regularization: a feasibility study.

Yingxuan Chen, Fang-Fang Yin, Yawei Zhang, You Zhang, Lei Ren

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Yingxuan ChenMedical Physics Graduate Program, Duke University, 2424 Erwin Road Suite 101, Durham, NC 27705, United States of America.
Fang-Fang YinMedical Physics Graduate Program, Duke University, 2424 Erwin Road Suite 101, Durham, NC 27705, United States of America.
Yawei ZhangDepartment of Radiation Oncology, Duke University Medical Center, DUMC Box 3295, Durham, NC 27710, United States of America.
You ZhangMedical Physics Graduate Program, Duke University, 2424 Erwin Road Suite 101, Durham, NC 27705, United States of America.
Lei RenMedical Physics Graduate Program, Duke University, 2424 Erwin Road Suite 101, Durham, NC 27705, United States of America.

Funding

A Limited-angle Intra-fractional Verification (LIVE) System for SBRT TreatmentsR01CA184173 · NCI · DUKE UNIVERSITY · PI REN, LEI, YIN, FANG-FANG · 2015 to 2018
$1.5M
NCI NIH HHS R01 CA184173
6 · The paper itself

Abstract

purposecompressed sensing reconstruction using total variation (TV) tends to over-smooth the edge information by uniformly penalizing the image gradient. The goal of this study is to develop a novel prior contour based TV (PCTV) method to enhance the edge information in compressed sensing reconstruction for CBCT.

methodsthe edge information is extracted from prior planning-CT via edge detection. Prior CT is first registered with on-board CBCT reconstructed with TV method through rigid or deformable registration. The edge contours in prior-CT is then mapped to CBCT and used as the weight map for TV regularization to enhance edge information in CBCT reconstruction. The PCTV method was evaluated using extended-cardiac-torso (XCAT) phantom, physical CatPhan phantom and brain patient data. Results were compared with both TV and edge preserving TV (EPTV) methods which are commonly used for limited projection CBCT reconstruction. Relative error was used to calculate pixel value difference and edge cross correlation was defined as the similarity of edge information between reconstructed images and ground truth in the quantitative evaluation.

resultscompared to TV and EPTV, PCTV enhanced the edge information of bone, lung vessels and tumor in XCAT reconstruction and complex bony structures in brain patient CBCT. In XCAT study using 45 half-fan CBCT projections, compared with ground truth, relative errors were 1.5%, 0.7% and 0.3% and edge cross correlations were 0.66, 0.72 and 0.78 for TV, EPTV and PCTV, respectively. PCTV is more robust to the projection number reduction. Edge enhancement was reduced slightly with noisy projections but PCTV was still superior to other methods. PCTV can maintain resolution while reducing the noise in the low mAs CatPhan reconstruction. Low contrast edges were preserved better with PCTV compared with TV and EPTV.

conclusionPCTV preserved edge information as well as reduced streak artifacts and noise in low dose CBCT reconstruction. PCTV is superior to TV and EPTV methods in edge enhancement, which can potentially improve the localization accuracy in radiation therapy.

Indexed as

AlgorithmsArtifactsBrainCone-Beam Computed TomographyFeasibility StudiesHumansImage Processing, Computer-AssistedImaging, Three-DimensionalPhantoms, ImagingRadiotherapy Planning, Computer-AssistedSpiral Cone-Beam Computed Tomography

Identifiers

PMID29537385
PMCPMC5947320

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.