Evidence map›Paper›PMID 29537331›Full record

ReviewInternational review of psychiatry (Abingdon, England)2018

Efficacy of early interventions for infants and young children with, and at risk for, autism spectrum disorders.

Rebecca J Landa

Registry-linked trialOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International review of psychiatry (Abingdon, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06125093 (Early Treatment for Children With Mental Health Problems and Genetic Abnormalities Through a Parenting Intervention), which is not on this map. Cited by 180 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
180citing papers in PubMed, 9 pooled it
16.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06125093 nacompletednot on this mapstarted 2023, after this paper: background citation

Early Treatment for Children With Mental Health Problems and Genetic Abnormalities Through a Parenting Intervention (The GAP): A Pragmatic Randomized Controlled Trial

TypeinterventionalSponsorFundació Sant Joan de DéuRan2023 to 2024Enrolled53ConditionsGenetic Syndrome, Language Development, Autism or Autistic Traits, ParentingArmsIncredible Years Autism Spectrum and Language Delays Parent Program (IY-ASLD®)
3 · Its place in the literature

Who cites it

180 citing papers in PubMed, 9 syntheses or guidelines pooled it, 382 citations in OpenAlex.

  1. Pooled it
  2. Nutritional Status of Children Diagnosed With Autism Spectrum Disorder: A Systematic Review and Meta-Analysis.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
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  9. Intervention Effects on Language in Children With Autism: A Project AIM Meta-Analysis.Journal of speech, language, and hearing research : JSLHR · 2020
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120 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Rebecca J Landaa Center for Autism and Related Disorders , Kennedy Krieger Institute , Baltimore , MD , USA.
Johns Hopkins University · US

Funding

Autism: Social And Communication Predictors in SiblingsR01MH059630 · NIMH · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI LANDA, REBECCA JEAN · 2001 to 2016
$10.7M
Preventive Dyadic Intervention to Enhance Communication Development in At-Risk InfantsR21DC015846 · NIDCD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI LANDA, REBECCA JEAN · 2017 to 2018
$444k
NIDCD NIH HHS R21 DC015846NIMH NIH HHS R01 MH059630
6 · The paper itself

Abstract

With advances in the field's ability to identify autism spectrum disorders (ASD) at younger ages, the need for information about the evidence-base for early intervention continues to rise. This review of the ASD early intervention (EI) literature focuses on efficacy studies published within the past 15 years. The neurodevelopmental context for early intervention, timing of initiating intervention, primary intervention approaches, and predictors of treatment outcomes are discussed. The evidence indicates that young children with ASD benefit from EI, and their parents learn to implement child-responsive engagement strategies when a parent-coaching intervention is provided. Evidence supports combining parent-mediated and direct clinician-implemented intervention to maximize child developmental gains. Clinical practice recommendations are presented, based on the literature reviewed.

Indexed as

Outcome Assessment, Health CareAutism Spectrum DisorderBehavior TherapyChildChild, PreschoolEarly Intervention, EducationalEarly Medical InterventionHumansInfantAutism spectrum disordersearly interventionefficacy

Identifiers

PMID29537331
PMCPMC6034700
OpenAlexW2792921834

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.