Evidence map›Paper›PMID 29537283›Full record

ArticleMolecular pharmaceutics2018

Noninvasive Trafficking of Brentuximab Vedotin and PET Imaging of CD30 in Lung Cancer Murine Models.

Lei Kang, Dawei Jiang, Emily B Ehlerding, Todd E Barnhart, Dalong Ni, Jonathan W Engle, Rongfu Wang, Peng Huang, Xiaojie Xu, Weibo Cai

Abstract read
In one paragraph

Article in Molecular pharmaceutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Radionuclide-based theranostics - a promising strategy for lung cancer.European journal of nuclear medicine and molecular imaging · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. European journal of nuclear medicine and molecular imaging · 2022
    Article
  11. Review
  12. Review
  13. Review
  14. Antibody-Drug Conjugates for Cancer Therapy.Molecules (Basel, Switzerland) · 2020
    Review
  15. Article
  16. Review
  17. Antibody-Based Tracers for PET/SPECT Imaging of Chronic Inflammatory Diseases.Chembiochem : a European journal of chemical biology · 2019
    Review
  18. ImmunoPET imaging of CD38 expression in hepatocellular carcinoma usingAmerican journal of translational research · 2019
    Article
  19. Immuno-PET imaging of VEGFR-2 expression in prostate cancer withAmerican journal of cancer research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Lei KangDepartment of Nuclear Medicine , Peking University First Hospital , Beijing 100034 , China.
Dawei JiangDepartment of Radiology , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.ORCID 0000-0002-4072-0075
Emily B EhlerdingDepartment of Medical Physics , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.
Todd E BarnhartDepartment of Medical Physics , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.
Dalong NiDepartment of Radiology , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.ORCID 0000-0001-6679-5414
Jonathan W EngleDepartment of Medical Physics , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.
Rongfu WangDepartment of Nuclear Medicine , Peking University First Hospital , Beijing 100034 , China.
Peng HuangGuangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Laboratory of Evolutionary Theranostics, School of Biomedical Engineering, Health Science Center , Shenzhen University , Shenzhen 518060 , China.ORCID 0000-0003-3651-7813
Xiaojie XuDepartment of Medical Molecular Biology , Beijing Institute of Biotechnology , Beijing 100850 , China.
Weibo CaiDepartment of Radiology , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.ORCID 0000-0003-4641-0833
University of Wisconsin–Madison · USPeking University · CNShenzhen University · CN

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
U.W. RADIOLOGICAL SCIENCES TRAINING PROGRAMT32CA009206 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Bryan Patrick Bednarz · 1985 to 2026
$12.1M
Chemistry-Biology Interface Training ProgramT32GM008505 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BLACKWELL, HELEN E. · 1993 to 2023
$9.8M
NCI NIH HHS P30 CA014520NCI NIH HHS T32 CA009206NIGMS NIH HHS T32 GM008505
6 · The paper itself

Abstract

CD30 has been considered a unique diagnostic and therapeutic target for CD30-positive lymphomas and some lung diseases. Additionally, CD30 has shown high expression in clinical lung cancer samples. In this study,

Indexed as

A549 CellsAnimalsBrentuximab VedotinCell Line, TumorDeferoxamineDisease Models, AnimalFemaleHumansImmunoconjugatesKi-1 AntigenLung NeoplasmsLymphomaMiceMice, NudePositron-Emission TomographyRadioisotopesBrentuximab VedotinDeferoxamineImmunoconjugatesKi-1 AntigenRadioisotopesZirconiumZirconium-89brentuximab vedotinCD30lung cancerpositron emission tomography (PET)Zr-89

Identifiers

PMID29537283
PMCPMC5920523
OpenAlexW2790096396

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.