ArticlePathogens and global health2018
Geographical distribution and molecular characterization for cutaneous leishmaniasis species by sequencing and phylogenetic analyses of kDNA and ITS1 loci markers in south-eastern Iran.
Article in Pathogens and global health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Geographical Distribution of Human Cutaneous and VisceralFrontiers in public health · 2021Pooled it
- Formulation and evaluation of amphotericin B emulsion gel against Leishmania major in a murine model: parasite burden, gene expression, and histopathological profiling.Parasitology research · 2026Article
- Molecular epidemiology, distribution, and determinants of cutaneous leishmaniasis in Northeast Ethiopia.Scientific reports · 2025Article
- In Vitro Anti-Leishmanial Activity and Molecular Docking of Eugenol as a Potential Agent Against Leishmania Major.Acta parasitologica · 2025Article
- Can archived lesion smears be used to identify Leishmania species in regions with high species diversity?Revista do Instituto de Medicina Tropical de Sao Paulo · 2025Article
- Canine leishmaniasis caused by Leishmania Tropica in southeastern Iran: a case series study.Scientific reports · 2024Article
- Six-Year Study on Cutaneous Leishmaniasis in Al-Muthanna, Iraq: Molecular Identification Using ITS1 Gene Sequencing.Infection & chemotherapy · 2024Article
- Genetic Diversity of Leishmania major Isolated from Different Dermal Lesions Using ITS2 Region.Acta parasitologica · 2024Article
- Molecular-based detection ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022Article
- Fifty years of struggle to control cutaneous leishmaniasis in the highest endemic county in Iran: A longitudinal observation inferred with interrupted time series model.PLoS neglected tropical diseases · 2022Article
- Performance of a universal PCR assay to identify different Leishmania species causative of Old World cutaneous leishmaniasis.Parasites & vectors · 2020Article
- Evaluation of a new live recombinant vaccine against cutaneous leishmaniasis in BALB/c mice.Parasites & vectors · 2020Article
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Authors and funding
10 authors.
Funding
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Abstract
This study aimed to explore geographic distribution and molecular characterization of cutaneous leishmaniasis (CL) species by amplifying two popular markers in kinetoplast DNA and internal transcribed spacer 1 loci by nested-PCR, and characterized by sequencing and phylogenetic analyses. Findings demonstrated that two species co-existed in the province: L. tropica (88.5%) and L. major (11.5%). All gender and age groups were equally infected, although males, 21-30 years old, exhibited a significantly higher infection. Sequencing and phylogenetic analyses of 34 randomly selected samples showed that L. tropica isolates exhibited some degree of heterogeneity. Both anthroponotic CL and zoonotic CL are present in south-eastern Iran with predominance of L. tropica species. Some level of heterogeneity was observed in L. tropica isolates which possibly reflects different colonies in the area. Implementation of diagnostic tools directly from clinical samples could be an important strategic approach for exploration of spatial distribution, molecular characterization and phylogenetic analyses.
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