Evidence map›Paper›PMID 29536351›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2019

Imaging of atherosclerosis, targeting LFA-1 on inflammatory cells with

E J Meester, B J Krenning, R H de Blois, J P Norenberg, M de Jong, M R Bernsen, K Van der Heiden

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Preclinical techniques to investigate exercise training in vascular pathophysiology.American journal of physiology. Heart and circulatory physiology · 2021
    Pooled it
  3. Review
  4. Review
  5. A SPECT-based method for dynamic imaging of the glymphatic system in rats.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  6. SPECT/CT imaging of inflammation and calcification in human carotid atherosclerosis to identify the plaque at risk of rupture.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  7. Review
  8. Transpathology: molecular imaging-based pathology.European journal of nuclear medicine and molecular imaging · 2021
    Review
  9. Article
  10. Article
  11. Diabetic vasculopathy: macro and microvascular injury.Current pathobiology reports · 2020
    Article
  12. Current and novel radiopharmaceuticals for imaging cardiovascular inflammation.The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... · 2020
    Review
  13. Imaging inflammation in atherosclerotic plaques: Just make it easy!Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  14. Review
  15. Antibody-Based Tracers for PET/SPECT Imaging of Chronic Inflammatory Diseases.Chembiochem : a European journal of chemical biology · 2019
    Review
  16. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

E J MeesterDepartment of Biomedical Engineering, Thorax Center, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
B J KrenningDepartment of Cardiology, Thorax Center, Erasmus Medical Center, Rotterdam, The Netherlands.
R H de BloisDepartment of Radiology & Nuclear Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
J P NorenbergRadiopharmaceutical Sciences, University of New Mexico, Albuquerque, NM, USA.
M de JongDepartment of Radiology & Nuclear Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
M R BernsenDepartment of Radiology & Nuclear Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
K Van der HeidenDepartment of Biomedical Engineering, Thorax Center, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands. k.vanderheiden@erasmusmc.nl.
Erasmus MC · NLUniversity of New Mexico · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMETHODS AND

resultsApoE

conclusionsOur results indicate the potential of radiolabeled DANBIRT as a relevant imaging radioligand for non-invasive evaluation of atherosclerotic inflammation.

Indexed as

AnimalsAntigens, CDAntigens, Differentiation, MyelomonocyticAzo CompoundsCD68 MoleculeFemaleHydantoinsImmunohistochemistryIndium RadioisotopesInflammationLymphocyte Function-Associated Antigen-1MiceMice, Inbred C57BLMice, Knockout, ApoEPlaque, AtheroscleroticSingle Photon Emission Computed Tomography Computed TomographyAntigens, CDAntigens, Differentiation, MyelomonocyticAzo CompoundsCD68 MoleculeCD68 protein, mouseDOTA-1-(4-aminobutyl)-5-(4-bromobenzyl)-3-(3,5-dichlorophenyl)-5-methylimidazolidine-2,4-dioneHydantoinsIndium-111Indium RadioisotopesLymphocyte Function-Associated Antigen-1oil red OAtherosclerosisinflammationmolecular imagingSPECT

Identifiers

PMID29536351
PMCPMC6775031
OpenAlexW2790594718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.