Evidence map›Paper›PMID 29536333›Full record

ArticleJournal of molecular neuroscience : MN2018

Association Study of VMAT1 Polymorphisms and Suicide Behavior.

Arezou Sayad, Rezvan Noroozi, Zahra Khodamoradi, Mir Davood Omrani, Mohammad Taheri, Soudeh Ghafouri-Fard

Abstract read
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In one paragraph

Article in Journal of molecular neuroscience : MN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Arezou SayadDepartment of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Rezvan NorooziPhytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Zahra KhodamoradiSchool of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Mir Davood OmraniDepartment of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammad TaheriDepartment of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran, Iran. mohamamd_823@yahoo.com.ORCID http://orcid.org/0000-0001-8381-0591
Soudeh Ghafouri-FardDepartment of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran, Iran. s.ghafourifard@sbmu.ac.ir.
Shahid Beheshti University of Medical Sciences · IRHamedan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic association studies have linked suicide behavior with genes encoding transporters of monoamine. Variants in the vesicular monoamine transporter 1 (VMAT1) have been previously shown to be associated with several psychiatric disorders including schizophrenia and bipolar disorder. However, their association with suicide behavior has not been explored. In the present study, we genotyped three single-nucleotide polymorphisms (rs2270637, rs1390938, and rs2279709) within this gene in 100 individuals who attempted suicide, 236 suicide victims, and 300 control subjects without any history of psychiatric disorders or suicide ideation. We demonstrated no difference in genotype, allele, or haplotype frequencies of theses single-nucleotide polymorphisms between the study groups. Consequently, contribution of VMAT1 in risk of psychiatric disorders might be independent of suicide behavior. Future studies with larger sample sizes are needed to confirm our results.

Indexed as

Polymorphism, Single NucleotideSuicideAdultCase-Control StudiesFemaleHumansMaleVesicular Monoamine Transport ProteinsSLC18A1 protein, humanVesicular Monoamine Transport ProteinsSNPSuicideVMAT1

Identifiers

PMID29536333
OpenAlexW2789762080

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.