Evidence map›Paper›PMID 29536322›Full record

ReviewHeart failure reviews2018

Infectious myocarditis: the role of the cardiac vasculature.

Linde Woudstra, Lynda J M Juffermans, Albert C van Rossum, Hans W M Niessen, Paul A J Krijnen

Open access · hybridAbstract readReview
In one paragraph

Review in Heart failure reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 42 citations in OpenAlex.

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  16. Coronary vasospasm: A narrative review.World journal of cardiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Linde WoudstraDepartment of Pathology, VU University Medical Center, (room 0E46), De Boelelaan 1117, 1081, HV, Amsterdam, The Netherlands. l.woudstra@vumc.nl.
Lynda J M JuffermansInstitute for Cardiovascular Research (ICaR-VU), VU University Medical Center, Amsterdam, The Netherlands.
Albert C van RossumInstitute for Cardiovascular Research (ICaR-VU), VU University Medical Center, Amsterdam, The Netherlands.
Hans W M NiessenDepartment of Pathology, VU University Medical Center, (room 0E46), De Boelelaan 1117, 1081, HV, Amsterdam, The Netherlands.
Paul A J KrijnenDepartment of Pathology, VU University Medical Center, (room 0E46), De Boelelaan 1117, 1081, HV, Amsterdam, The Netherlands.
Amsterdam UMC Location VUmc · NLNetherlands Heart Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious myocarditis is the result of an immune response to a microbial infection of the heart. The blood vessels of the heart, both the intramyocardial microvasculature and the large epicardial coronary arteries, play an important role in the pathogenesis of infectious myocarditis. First of all, in addition to cardiomyocytes, endothelial cells of the cardiac (micro)vasculature are direct targets for infection. Moreover, through the expression of adhesion molecules and antigen presenting Major Histocompatibility Complex molecules, the blood vessels assist in shaping the cellular immune response in infectious myocarditis. In addition, damage and dysfunction of the cardiac (micro)vasculature are associated with thrombus formation as well as aberrant regulation of vascular tone including coronary vasospasm. These in turn can cause cardiac perfusion abnormalities and even myocardial infarction. In this review, we will discuss the role of the cardiac (micro)vasculature in the pathogenesis of infectious myocarditis.

Indexed as

Coronary VesselsEndothelium, VascularHumansInfectionsMyocarditisMyocytes, CardiacEndothelial cellsInfectionMyocardial infarctionMyocarditisVasculature

Identifiers

PMID29536322
PMCPMC6010496
OpenAlexW2789414958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.