ArticleEuropean radiology2018
Presence of multi-segment clot sign on dynamic CT angiography: a predictive imaging marker of recanalisation and good outcome in acute ischaemic stroke patients.
Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
- Multi-Mode Imaging Scale for Endovascular Therapy in Patients with Acute Ischemic Stroke (META).Brain sciences · 2022Article
- Can imaging extend the thrombolytic time window after stroke?Nature reviews. Neurology · 2019Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
objectiveTo investigate the value of multi-segment clot (MSC) sign on dynamic CT angiography (CTA) in predicting recanalisation and outcome after reperfusion therapy in acute ischaemic stroke (AIS) with large artery occlusion (LAO).
methodsWe retrospectively reviewed data of anterior circulation LAO patients from a prospectively collected database for consecutive AIS patients who underwent perfusion CT (CTP) before treatment. MSC sign was defined as the presence of multiple segments on dynamic CTA derived from CTP data. Good outcome was defined as modified Rankin score 0-3 at 90 days.
resultsA total of 181 LAO patients were enrolled. MSC sign was present in 73 (40.3%) patients. When compared with patients without MSC sign, patients with MSC sign had a significantly higher rate of recanalisation (76.7% versus 56.5%, p = 0.005) and good outcome (67.1% versus 51.0%, p = 0.035). Multivariable logistic regression analyses showed that MSC sign was an independent predictor for both recanalisation (OR [95% CI] = 2.237 [1.069-4.681]; p = 0.033) and good outcome (OR [95% CI] = 2.715 [1.154-6.388]; p = 0.022) after adjustment.
conclusionsThe MSC sign is a good indicator for recanalisation and good outcome after reperfusion therapy in anterior circulation LAO patients. KEY POINTS: • MSC sign was present in about 40% acute anterior circulation LAO patients. • MSC sign is a predictor for recanalisation after reperfusion treatment. • Patients with MSC sign have a better outcome.
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