Evidence map›Paper›PMID 29536242›Full record

ArticleEuropean radiology2018

The relationship between applied energy and ablation zone volume in patients with hepatocellular carcinoma and colorectal liver metastasis.

Wouter J Heerink, A Millad Solouki, Rozemarijn Vliegenthart, Simeon J S Ruiter, Egbert Sieders, Matthijs Oudkerk, Koert P de Jong

Abstract read
In one paragraph

Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wouter J HeerinkDepartment of Radiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands. w.j.heerink@umcg.nl.ORCID http://orcid.org/0000-0002-5629-1359
A Millad SoloukiDepartment of Radiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.
Rozemarijn VliegenthartDepartment of Radiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.
Simeon J S RuiterDepartment of HPB Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Egbert SiedersDepartment of HPB Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Matthijs OudkerkCenter for Medical Imaging North East Netherlands, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Koert P de JongCenter for Medical Imaging North East Netherlands, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Funding

Samenwerkingsverband Noord-Nederland T2017
6 · The paper itself

Abstract

objectivesTo study the ratio of ablation zone volume to applied energy in computed tomography (CT)-guided radiofrequency ablation (RFA) and microwave ablation (MWA) in patients with hepatocellular carcinoma (HCC) in a cirrhotic liver and in patients with colorectal liver metastasis (CRLM).

methodsIn total, 90 liver tumors, 45 HCCs in a cirrhotic liver and 45 CRLMs were treated with RFA or with one of two MWA devices (MWA_A and MWA_B), resulting in 15 procedures for each tumor type, per device. Device settings were recorded and the applied energy was calculated. Ablation volumes were segmented on the contrast-enhanced CT scans obtained 1 week after the procedure. The ratio of ablation zone volume in milliliters to applied energy in kilojoules was determined for each procedure and compared between HCC (R

resultsWith RFA, R

conclusionsWith RFA, there was no significant difference in energy deposition ratio between tumor types. With both MWA devices, the ratios were higher for HCCs. Tailoring microwave ablation device protocols to tumor type might prevent incomplete ablations. KEY POINTS: • HCCs and CRLMs respond differently to microwave ablation • For MWA, CRLMs required more energy to achieve a similar ablation volume • Tailoring ablation protocols to tumor type might prevent incomplete ablations.

Indexed as

AgedCarcinoma, HepatocellularCatheter AblationColorectal NeoplasmsDiathermyFemaleHumansLiver NeoplasmsMaleMargins of ExcisionMicrowavesMiddle AgedRetrospective StudiesTomography, X-Ray ComputedAblation techniquesCarcinoma, HepatocellularLiver diseasesMultidetector computed tomographyRadiology, Interventional

Identifiers

PMID29536242
PMCPMC6028841

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.