Evidence map›Paper›PMID 29536240›Full record

ArticleEuropean radiology2018

Glioma imaging in Europe: A survey of 220 centres and recommendations for best clinical practice.

S C Thust, S Heiland, A Falini, H R Jäger, A D Waldman, P C Sundgren, C Godi, V K Katsaros, A Ramos, N Bargallo and 4 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06551909 (Radioimmunotherapy in Solid Tumors), which is not on this map. Cited by 121 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06551909 narecruitingnot on this mapstarted 2024, after this paper: background citation

Radioimmunotherapy in Solid Tumors (Aim 2- Stereotactic Neoadjuvant Radiotherapy for Glioblastoma)

TypeinterventionalSponsorIRCCS San RaffaeleRan2024 to 2027Enrolled30ConditionsGlioblastomaArmsNeoaddjuvant Stereotactic Radiotherapy with Simultaneous Integrated Boost
3 · Its place in the literature

Who cites it

121 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Interventions to reduce the time to diagnosis of brain tumours.The Cochrane database of systematic reviews · 2020
    Pooled it
  3. Annals of nuclear medicine · 2025
    Trial
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  6. Review
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  19. Automated Diffusion Analysis for Noninvasive Prediction ofAJNR. American journal of neuroradiology · 2025
    Article
  20. Review

61 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

S C ThustLysholm Neuroradiology Department, National Hospital for Neurology and Neurosurgery, London, UK.
S HeilandDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.
A FaliniDepartment of Neuroradiology, San Raffaele Scientific Institute, Milan, Italy.
H R JägerLysholm Neuroradiology Department, National Hospital for Neurology and Neurosurgery, London, UK.
A D WaldmanNeuroimaging Sciences, University of Edinburgh, Edinburgh, UK.
P C SundgrenInstitution for Clinical Sciences/Radiology, Lund University, Lund, Sweden.
C GodiDepartment of Neuroradiology, San Raffaele Scientific Institute, Milan, Italy.
V K KatsarosGeneral Anti-Cancer and Oncological Hospital "Agios Savvas", Athens, Greece.
A RamosHospital 12 de Octubre, Madrid, Spain.
N BargalloImage Diagnostic Centre, Hospital Clinic de Barcelona, Barcelona, Spain.
M W VernooijDepartment of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.
T YousryLysholm Neuroradiology Department, National Hospital for Neurology and Neurosurgery, London, UK.
M BendszusDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.
M SmitsDepartment of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands. marion.smits@erasmusmc.nl.ORCID http://orcid.org/0000-0001-5563-2871

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAt a European Society of Neuroradiology (ESNR) Annual Meeting 2015 workshop, commonalities in practice, current controversies and technical hurdles in glioma MRI were discussed. We aimed to formulate guidance on MRI of glioma and determine its feasibility, by seeking information on glioma imaging practices from the European Neuroradiology community.

methodsInvitations to a structured survey were emailed to ESNR members (n=1,662) and associates (n=6,400), European national radiologists' societies and distributed via social media.

resultsResponses were received from 220 institutions (59% academic). Conventional imaging protocols generally include T2w, T2-FLAIR, DWI, and pre- and post-contrast T1w. Perfusion MRI is used widely (85.5%), while spectroscopy seems reserved for specific indications. Reasons for omitting advanced imaging modalities include lack of facility/software, time constraints and no requests. Early postoperative MRI is routinely carried out by 74% within 24-72 h, but only 17% report a percent measure of resection. For follow-up, most sites (60%) issue qualitative reports, while 27% report an assessment according to the RANO criteria. A minority of sites use a reporting template (23%).

conclusionClinical best practice recommendations for glioma imaging assessment are proposed and the current role of advanced MRI modalities in routine use is addressed. KEY POINTS: • We recommend the EORTC-NBTS protocol as the clinical standard glioma protocol. • Perfusion MRI is recommended for diagnosis and follow-up of glioma. • Use of advanced imaging could be promoted with increased education activities. • Most response assessment is currently performed qualitatively. • Reporting templates are not widely used, and could facilitate standardisation.

Indexed as

Brain NeoplasmsEuropeFeasibility StudiesFemaleGliomaHumansImaging, Three-DimensionalMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMalePractice Guidelines as TopicPractice Patterns, Physicians'Surveys and QuestionnairesBrain neoplasmsGliomaGuidelineMagnetic resonance imagingSurveys and questionnaires

Identifiers

PMID29536240
PMCPMC6028837

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.