Evidence map›Paper›PMID 29536198›Full record

ArticleJournal of bone and mineral metabolism2019

Gender differences in anti-osteoporosis drug treatment after osteoporotic fractures.

Youn Jung, Yeonhee Ko, Ha Young Kim, Yong Chan Ha, Young-Kyun Lee, Tae-Young Kim, Dong-Soo Choo, Sunmee Jang

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of bone and mineral metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Male osteoporosis.Archives of endocrinology and metabolism · 2022
    Review
  6. Article
  7. Development of the Asia Pacific Consortium on Osteoporosis (APCO) Framework: clinical standards of care for the screening, diagnosis, and management of osteoporosis in the Asia-Pacific region.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Article
  8. Secondary prevention of fragility fractures in Asia Pacific: an educational initiative.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Review
  9. Article
  10. Article
  11. Article
  12. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 1 country.

Youn JungKorea Institute for Health and Social Affairs, Sejong, Republic of Korea.
Yeonhee KoGachon University Gil Medical Center, Incheon, South Korea.
Ha Young KimDepartment of Internal Medicine, Wonkwang University Sanbon Hospital, Gunpo, South Korea.
Yong Chan HaDepartment of Orthopaedic Surgery, Chung-Ang University College of Medicine, Seoul, South Korea.
Young-Kyun LeeDepartment of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seongnam, South Korea.
Tae-Young KimDepartment of Orthopaedic Surgery, Konkuk University Hospital, School of Medicine, Konkuk University, Seoul, South Korea.
Dong-Soo ChooBig Data Steering Department, National Health Insurance Service, Wonju, South Korea.
Sunmee JangCollege of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, 191 Hambakmoei-ro, Yeonsu-gu, Incheon, 21936, South Korea. smjang@gahcon.ac.kr.
Chung-Ang University · KRGachon University · KRGachon University Gil Medical Center · KRKonkuk University Medical Center · KRKorea Institute for Health and Social Affairs · KRNational Health Insurance Service · KRSeoul National University Bundang Hospital · KRWonkwang University · KR

Funding

Ministry of Health and Welfare HI13C1522
6 · The paper itself

Abstract

This study examined differences between men and women in factors affecting anti-osteoporosis drug treatment after osteoporotic fracture. Using a national claims database, we analyzed patients aged 50 years and older who experienced their first osteoporotic fracture between January 1, 2008, and December 31, 2012. We examined whether patients were prescribed anti-osteoporosis drugs within 6 months post-fracture. Factors associated with treatment status were identified using multivariate logistic regression. Among a total of 556,410 patients aged 50 and older, only 37% were prescribed anti-osteoporosis drugs within 6 months post-fracture. Female patients with fractures were more likely to receive pharmacotherapy than male patients (41.7 vs. 19.3%). Older age significantly increased the likelihood of receiving anti-osteoporosis drugs after osteoporotic fracture. For men, the adjusted odds ratio for receiving therapy was greatest in those aged 80 years and older (OR 6.4), and for women, it was largest in those aged 70-79 (OR 3.33). Both men and women were more likely to be prescribed drugs after a spine fracture, with men having significantly greater odds of receiving drug therapy (men, OR 7.1, 95% CI 6.5-7.9; women 4.79, CI 4.63-4.96). Patients with rheumatic disease or other osteoporosis-inducing comorbid disease were more likely to be prescribed anti-osteoporosis drugs. Our findings indicate that a lack of anti-osteoporosis pharmacotherapy after fracture remains a problem in Korea, especially among men, highlighting the need for effective quality improvement interventions to maximize post-fracture treatment rates.

Indexed as

Sex CharacteristicsAgedBone Density Conservation AgentsFemaleHumansLogistic ModelsMaleMultivariate AnalysisOsteoporotic FracturesRepublic of KoreaSex FactorsBone Density Conservation AgentsFracturesGender differencesOsteoporosisPharmacotherapyPost-fracture treatment

Identifiers

PMID29536198
OpenAlexW2791023573

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.