Evidence map›Paper›PMID 29536194›Full record

ArticleWorld journal of microbiology & biotechnology2018

Metabolic engineering of arginine permeases to reduce the formation of urea in Saccharomyces cerevisiae.

Peng Zhang, Xing Hu

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of microbiology & biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Next Generation Winemakers: Genetic Engineering inBioengineering (Basel, Switzerland) · 2020
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Peng ZhangState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, 330047, China.
Xing HuState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, 330047, China. hx0726@ncu.edu.cn.
Nanchang University · CN

Funding

National Natural Science Foundation of China (CN) 21276109National Natural Science Foundation of China (CN) 21390204the Agriculture Project of Jiangxi Provincial Department of Science and Technology 20171BBF60044
6 · The paper itself

Abstract

Urea is an important precursor of the harmful carcinogenic product ethyl carbamate in fermented wines. To decipher more fully the contributions of three arginine permeases, Can1p, Gap1p and Alp1p in urea formation, various engineered strains were examined for their ability to form urea. This included seven mutants with different combinations of permease deficiency and grown in both simple and more complex media, and the wild-type strain modified to overexpress the three arginine permeases. A truncated GATA transcription factor, Gln3p

Indexed as

Metabolic EngineeringAmino AcidsAmino Acid Transport SystemsAmino Acid Transport Systems, BasicArginineCulture MediaFermentationGene Expression Regulation, FungalMutationSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsTransformation, GeneticUreaUrethaneWineAmino AcidsAmino Acid Transport SystemsAmino Acid Transport Systems, BasicArgininearginine permeaseCulture MediaSaccharomyces cerevisiae ProteinsTranscription FactorsUreaUrethaneArginine uptakeBrewingEthyl carbamateGln3pNitrogen catabolite repression

Identifiers

PMID29536194
OpenAlexW2789510021

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.