ArticleScience advances2018
Article in Science advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- One hundred years of spin: Fundamental physics, dark matter, exotic interactions, and all that.Science advances · 2026Review
- Hyperpolarization of PyridineAngewandte Chemie (International ed. in English) · 2026Article
- HyperpolarizedACS sensors · 2026Article
- Molecular Fragmentation as a Strategy to Access Hyperpolarized Compounds from Para-Hydrogen.Chemphyschem : a European journal of chemical physics and physical chemistry · 2025Article
- Unconventional Parahydrogen-Induced Hyperpolarization Effects in Chemistry and Catalysis: From Photoreactions to Enzymes.ACS catalysis · 2025Review
- Bioorthogonal Janus microparticles for photothermal and chemo-therapy.Smart medicine · 2024Article
- Metal-Mediated Catalytic Polarization Transfer fromACS catalysis · 2024Article
- The Application of Bio-orthogonality for In Vivo Animal Imaging.Chemical & biomedical imaging · 2023Review
- Proton-Only Sensing of Hyperpolarized [1,2-ACS sensors · 2022Article
- Design and Characterization of HyperpolarizedACS sensors · 2022Article
- Article
- Pd-based bimetallic catalysts for parahydrogen-induced polarization in heterogeneous hydrogenations.Magnetic resonance (Gottingen, Germany) · 2021Article
- Parahydrogen-Induced Hyperpolarization of Gases.Angewandte Chemie (International ed. in English) · 2020Review
- Infinite-order perturbative treatment for quantum evolution with exchange.Science advances · 2020Article
- Multiple Quantum Coherences Hyperpolarized at Ultra-Low Fields.Chemphyschem : a European journal of chemical physics and physical chemistry · 2019Article
- Experimental evidence for the role of paramagnetic oxygen concentration on the decay of long-lived nuclear spin order.RSC advances · 2019Article
- Unlocking a Diazirine Long-Lived Nuclear Singlet State via Photochemistry: NMR Detection and Lifetime of an Unstabilized Diazo-Compound.Journal of the American Chemical Society · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Hyperpolarized magnetic resonance (HP-MR) is a powerful, sensitive, and noninvasive approach to visualize molecular structure, function, and dynamics in vitro and in vivo. Current applications of HP-MR mostly rely on hyperpolarization of target compounds in dedicated hyperpolarizers because biomolecules can typically not be hyperpolarized directly in vivo. The injected hyperpolarized probes often undergo multiple metabolic pathways in living systems, and it remains challenging to localize and identify specific targets with high chemical selectivity. To address these current limitations in HP-MR, we report a novel hyperpolarization tagging strategy that integrates bioorthogonal chemistry and hyperpolarization to achieve the specific hyperpolarization of targets. This strategy is demonstrated by studies of hyperpolarized
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.