Evidence map›Paper›PMID 29535976›Full record

ArticleFrontiers in cellular and infection microbiology2018

Hypoacylated LPS from Foodborne Pathogen

Kirill V Korneev, Anna N Kondakova, Ekaterina N Sviriaeva, Nikita A Mitkin, Angelo Palmigiano, Andrey A Kruglov, Georgy B Telegin, Marina S Drutskaya, Luisa Sturiale, Domenico Garozzo and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. mBio · 2025
    Article
  3. Article
  4. rs71327024 Associated with COVID-19 Hospitalization ReducesInternational journal of molecular sciences · 2023
    Article
  5. Review
  6. Review
  7. Shotgun Bacterial Lipid A Analysis Using Routine MALDI-TOF Mass Spectrometry.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  8. Article
  9. Review
  10. Human Immunity AgainstImmune network · 2019
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Kirill V KorneevEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Anna N KondakovaZelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Ekaterina N SviriaevaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Nikita A MitkinEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Angelo PalmigianoCNR Institute for Polymers Composites and Biomaterials, Catania, Italy.
Andrey A KruglovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Georgy B TeleginBranch of Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Pushchino, Russia.
Marina S DrutskayaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Luisa SturialeCNR Institute for Polymers Composites and Biomaterials, Catania, Italy.
Domenico GarozzoCNR Institute for Polymers Composites and Biomaterials, Catania, Italy.
Sergei A NedospasovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Yuriy A KnirelZelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Dmitry V KuprashEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Engelhardt Institute of Molecular Biology · RUInstitute of Polymers, Composites and Biomaterials · ITLomonosov Moscow State University · RUN.D. Zelinsky Institute of Organic Chemistry · RUGerman Rheumatism Research Centre · DEInstitute of Bioorganic Chemistry · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toll-like receptor 4 (TLR4) initiates immune response against Gram-negative bacteria upon specific recognition of lipid A moiety of lipopolysaccharide (LPS), the major component of their cell wall. Some natural differences between LPS variants in their ability to interact with TLR4 may lead to either insufficient activation that may not prevent bacterial growth, or excessive activation which may lead to septic shock. In this study we evaluated the biological activity of LPS isolated from pathogenic strain of

Indexed as

AnimalsCampylobacter jejuniCytokinesFoodborne DiseasesInterferon Regulatory Factor-3Interleukin-1betaInterleukin-6Lipid ALipopolysaccharidesMacrophagesMiceMice, Inbred C57BLRNA, Small InterferingToll-Like Receptor 4Tumor Necrosis Factor-alphaCytokinesInterferon Regulatory Factor-3Interleukin-1betaInterleukin-6Irf3 protein, mouseLipid ALipopolysaccharidesRNA, Small InterferingTlr4 protein, mouseToll-Like Receptor 4Tumor Necrosis Factor-alphaacyl chainsCampylobacter jejunilipid ALPSmacrophagespathogenic bacteriaproinflammatory cytokinesTLR4

Identifiers

PMID29535976
PMCPMC5835049
OpenAlexW2790498644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.