Evidence map›Paper›PMID 29535734›Full record

ReviewFrontiers in immunology2018

The Role of Natural Killer T Cells in Cancer-A Phenotypical and Functional Approach.

Daniëlle Krijgsman, Marianne Hokland, Peter J K Kuppen

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 142 papers.

0numbers the graph read from it
0cells of the map it votes in
142citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

142 citing papers in PubMed, 232 citations in OpenAlex.

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  11. Immunopathogenesis of Sarcoidosis.Seminars in respiratory and critical care medicine · 2025
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  19. Chemokines that govern T cell activity in tumors.Current opinion in immunology · 2025
    Review
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82 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Daniëlle KrijgsmanDepartment of Surgery, Leiden University Medical Center, Leiden, Netherlands.
Marianne HoklandDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Peter J K KuppenDepartment of Surgery, Leiden University Medical Center, Leiden, Netherlands.
Aarhus University · DKLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer T (NKT) cells are a subset of CD1d-restricted T cells at the interface between the innate and adaptive immune system. NKT cells can be subdivided into functional subsets that respond rapidly to a wide variety of glycolipids and stress-related proteins using T- or natural killer (NK) cell-like effector mechanisms. Because of their major modulating effects on immune responses

Indexed as

AnimalsCarcinogenesisGlycolipidsHumansImmune ToleranceImmunizationImmunotherapyNatural Killer T-CellsNeoplasmsT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsGlycolipidscancerimmune escapeimmunotherapynatural killer T cellstumor immunology

Identifiers

PMID29535734
PMCPMC5835336
OpenAlexW2793229570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.