Evidence map›Paper›PMID 29535731›Full record

ArticleFrontiers in immunology2018

NLRX1 Modulates Immunometabolic Mechanisms Controlling the Host-Gut Microbiota Interactions during Inflammatory Bowel Disease.

Andrew Leber, Raquel Hontecillas, Nuria Tubau-Juni, Victoria Zoccoli-Rodriguez, Vida Abedi, Josep Bassaganya-Riera

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 63 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. The gut as a central hub for multi-organ crosstalk in aging.Cellular and molecular life sciences : CMLS · 2026
    Review
  5. Therapeutic effect ofFrontiers in pharmacology · 2026
    Article
  6. Article
  7. Review
  8. The Application of Organoids in the Study of Antiviral Innate Immunity.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. The epithelium takes the stage in asthma and inflammatory bowel diseases.Frontiers in cell and developmental biology · 2024
    Review
  16. Article
  17. Review
  18. NADAntioxidants (Basel, Switzerland) · 2023
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Andrew LeberLandos Biopharma, Inc., Blacksburg, VA, United States.
Raquel HontecillasLandos Biopharma, Inc., Blacksburg, VA, United States.
Nuria Tubau-JuniNutritional Immunology and Molecular Medicine Laboratory, Biocomplexity Institute of Virginia Tech, Blacksburg, VA, United States.
Victoria Zoccoli-RodriguezLandos Biopharma, Inc., Blacksburg, VA, United States.
Vida AbediNutritional Immunology and Molecular Medicine Laboratory, Biocomplexity Institute of Virginia Tech, Blacksburg, VA, United States.
Josep Bassaganya-RieraLandos Biopharma, Inc., Blacksburg, VA, United States.
Virginia Tech · USBiocom · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interactions among the gut microbiome, dysregulated immune responses, and genetic factors contribute to the pathogenesis of inflammatory bowel disease (IBD).

Indexed as

AnimalsCells, CulturedColitisDextran SulfateDietary SupplementsDisease Models, AnimalEpithelial CellsEubacterialesGastrointestinal MicrobiomeGlutamineHumansImmunity, InnateInflammationInflammatory Bowel DiseasesMiceMice, Inbred C57BLDextran SulfateGlutamineMitochondrial ProteinsNLRX1 protein, mousegut microbiomeimmunometabolisminflammatory bowel diseaseintestinal epithelial cellsmucosal immunologyNLRX1

Identifiers

PMID29535731
PMCPMC5834749
OpenAlexW2793905278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.