Evidence map›Paper›PMID 29535713›Full record

ReviewFrontiers in immunology2018

Vaccines for Leprosy and Tuberculosis: Opportunities for Shared Research, Development, and Application.

Mariateresa Coppola, Susan J F van den Eeden, Naoko Robbins, Louis Wilson, Kees L M C Franken, Linda B Adams, Tom P Gillis, Tom H M Ottenhoff, Annemieke Geluk

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. Article
  3. IFN-γ-Driven macrophage responses in the immunity toFrontiers in cellular and infection microbiology · 2025
    Review
  4. Leprosy.Nature reviews. Disease primers · 2024
    Review
  5. Unlocking Opportunities forACS infectious diseases · 2024
    Review
  6. Review
  7. Article
  8. A Bibliometric Analysis of Leprosy during 2000-2021 from Web of Science Database.International journal of environmental research and public health · 2022
    Article
  9. Review
  10. Review
  11. Review
  12. Le infezioni in medicina · 2021
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Mariateresa CoppolaDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Susan J F van den EedenDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Naoko RobbinsThe National Hansen's Disease Programs, Baton Rouge, LA, United States.
Louis WilsonDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Kees L M C FrankenDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Linda B AdamsThe National Hansen's Disease Programs, Baton Rouge, LA, United States.
Tom P GillisThe National Hansen's Disease Programs, Baton Rouge, LA, United States.
Tom H M OttenhoffDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Annemieke GelukDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Leiden University Medical Center · NLNational Hansen's Disease Program · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) and leprosy still represent significant public health challenges, especially in low- and lower middle-income countries. Both poverty-related mycobacterial diseases require better tools to improve disease control. For leprosy, there has been an increased emphasis on developing tools for improved detection of infection and early diagnosis of disease. For TB, there has been a similar emphasis on such diagnostic tests, while increased research efforts have also focused on the development of new vaccines. Bacille Calmette-Guérin (BCG), the only available TB vaccine, provides insufficient and inconsistent protection to pulmonary TB in adults. The impact of BCG on leprosy, however, is significant, and the introduction of new TB vaccines that might replace BCG could, therefore, have serious impact also on leprosy. Given the similarities in antigenic makeup between the pathogens

Indexed as

LeprosyTuberculosis, PulmonaryTuberculosis VaccinesAnimalsAntigens, BacterialBacterial ProteinsCross ProtectionDisease Models, AnimalHumansMiceMycobacterium lepraeMycobacterium tuberculosisAntigens, BacterialBacterial ProteinsESAT-6 protein, Mycobacterium tuberculosisTuberculosis Vaccinesantigen 85Bearly secretory antigenic targethybrid recombinant proteinleprosyMycobacterium lepraeMycobacterium tuberculosistuberculosisvaccines

Identifiers

PMID29535713
PMCPMC5834475
OpenAlexW2790008783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.