Evidence map›Paper›PMID 29535711›Full record

ArticleFrontiers in immunology2018

The Cholinergic and Adrenergic Autocrine Signaling Pathway Mediates Immunomodulation in Oyster

Zhaoqun Liu, Lingling Wang, Zhao Lv, Zhi Zhou, Weilin Wang, Meijia Li, Qilin Yi, Limei Qiu, Linsheng Song

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Zhaoqun LiuLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, China.
Lingling WangLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, China.
Zhao LvKey Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China.
Zhi ZhouKey Laboratory of Tropical Biological Resources of Ministry of Education, Hainan University, Haikou, China.
Weilin WangLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, China.
Meijia LiKey Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China.
Qilin YiLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, China.
Limei QiuKey Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China.
Linsheng SongLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, China.
Dalian Ocean University · CNChinese Academy of Sciences · CNQingdao National Laboratory for Marine Science and Technology · CNHainan University · CNUniversity of Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is becoming increasingly clear that neurotransmitters impose direct influence on regulation of the immune process. Recently, a simple but sophisticated neuroendocrine-immune (NEI) system was identified in oyster, which modulated neural immune response

Indexed as

AcetylcholineAnimalsAutocrine CommunicationCrassostreaHemocytesNeuroimmunomodulationNeurosecretory SystemsNorepinephrineSignal TransductionAcetylcholineNorepinephrineautocrine/paracrineCrassostrea gigashemocyteimmune regulationmembrane receptorneurotransmitter

Identifiers

PMID29535711
PMCPMC5834419
OpenAlexW2792809997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.