Evidence map›Paper›PMID 29535709›Full record

ArticleFrontiers in immunology2018

A Context-Dependent Role for αv Integrins in Regulatory T Cell Accumulation at Sites of Inflammation.

Iris Mair, Stephanie E J Zandee, Iqbal S Toor, Louise Saul, Rhoanne C McPherson, Melanie D Leech, Danielle J Smyth, Richard A O'Connor, Neil C Henderson, Stephen M Anderton

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Tuning immunity through tissue mechanotransduction.Nature reviews. Immunology · 2023
    Review
  7. Article
  8. PI3K in T Cell Adhesion and Trafficking.Frontiers in immunology · 2021
    Review
  9. Article
  10. The immune response is a prerequisite for the development of CD4International journal of clinical and experimental pathology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Iris MairMRC Centre for Inflammation Research, Centre for Multiple Sclerosis Research, BHF Centre for Cardiovascular Science, and Centre for Immunity Infection and Evolution, University of Edinburgh, Edinburgh, United Kingdom.
Stephanie E J ZandeeMRC Centre for Inflammation Research, Centre for Multiple Sclerosis Research, BHF Centre for Cardiovascular Science, and Centre for Immunity Infection and Evolution, University of Edinburgh, Edinburgh, United Kingdom.
Iqbal S ToorMRC Centre for Inflammation Research, Centre for Multiple Sclerosis Research, BHF Centre for Cardiovascular Science, and Centre for Immunity Infection and Evolution, University of Edinburgh, Edinburgh, United Kingdom.
Louise SaulMRC Centre for Inflammation Research, Centre for Multiple Sclerosis Research, BHF Centre for Cardiovascular Science, and Centre for Immunity Infection and Evolution, University of Edinburgh, Edinburgh, United Kingdom.
Rhoanne C McPhersonMRC Centre for Inflammation Research, Centre for Multiple Sclerosis Research, BHF Centre for Cardiovascular Science, and Centre for Immunity Infection and Evolution, University of Edinburgh, Edinburgh, United Kingdom.
Melanie D LeechMRC Centre for Inflammation Research, Centre for Multiple Sclerosis Research, BHF Centre for Cardiovascular Science, and Centre for Immunity Infection and Evolution, University of Edinburgh, Edinburgh, United Kingdom.
Danielle J SmythMRC Centre for Inflammation Research, Centre for Multiple Sclerosis Research, BHF Centre for Cardiovascular Science, and Centre for Immunity Infection and Evolution, University of Edinburgh, Edinburgh, United Kingdom.
Richard A O'ConnorMRC Centre for Inflammation Research, Centre for Multiple Sclerosis Research, BHF Centre for Cardiovascular Science, and Centre for Immunity Infection and Evolution, University of Edinburgh, Edinburgh, United Kingdom.
Neil C HendersonMRC Centre for Inflammation Research, Centre for Multiple Sclerosis Research, BHF Centre for Cardiovascular Science, and Centre for Immunity Infection and Evolution, University of Edinburgh, Edinburgh, United Kingdom.
Stephen M AndertonMRC Centre for Inflammation Research, Centre for Multiple Sclerosis Research, BHF Centre for Cardiovascular Science, and Centre for Immunity Infection and Evolution, University of Edinburgh, Edinburgh, United Kingdom.
University of Edinburgh · GBCentre for Immunity, Infection and Evolution · GBCentre for Inflammation Research · GB

Funding

Medical Research Council G0901697Medical Research Council G1100084Medical Research Council MR/M00242X/1Wellcome Trust 103749
6 · The paper itself

Abstract

Several inflammatory diseases including multiple sclerosis and inflammatory bowel disease have been associated with dysfunctional and/or reduced numbers of Foxp3

Indexed as

AnimalsAutoimmune DiseasesColitisEncephalomyelitis, Autoimmune, ExperimentalInflammationIntegrin alphaVMiceMice, KnockoutT-Lymphocytes, RegulatoryIntegrin alphaVautoimmune diseasecolitisexperimental autoimmune encephalomyelitisFoxp3inflammationintegrin αvregulatory T cellresolution of inflammation

Identifiers

PMID29535709
PMCPMC5834440
OpenAlexW2788424353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.