Evidence map›Paper›PMID 29535688›Full record

ArticleFrontiers in microbiology2018

Conceptual Perspectives: Bacterial Antimicrobial Peptide Induction as a Novel Strategy for Symbiosis with the Human Host.

Santosh K Ghosh, Zhimin Feng, Hisashi Fujioka, Renate Lux, Thomas S McCormick, Aaron Weinberg

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
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  8. Heat-KilledMicroorganisms · 2024
    Article
  9. Article
  10. PeriodontopathogensPathogens (Basel, Switzerland) · 2023
    Review
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  15. Frontiers in microbiology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Santosh K GhoshBiological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States.
Zhimin FengBiological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States.
Hisashi FujiokaElectron Microscopy Core, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Renate LuxSchool of Dentistry, University of California, Los Angeles, Los Angeles, CA, United States.
Thomas S McCormickBiological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States.
Aaron WeinbergBiological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States.
Case Western Reserve University · USUniversity of California, Los Angeles · US

Funding

Ontogeny Of Oral Epithelial Antimicrobial PeptidesR01DE018276 · NIDCR · CASE WESTERN RESERVE UNIVERSITY · PI WEINBERG, AARON · 2007 to 2015
$3.5M
Fusobacterial Associated Beta Defensin InducerR56DE018276 · NIDCR · CASE WESTERN RESERVE UNIVERSITY · PI WEINBERG, AARON · 2016 to 2016
$475k
NIDCR NIH HHS R01 DE018276NIDCR NIH HHS R56 DE018276
6 · The paper itself

Abstract

Human beta defensins (hBDs) are small cationic peptides, expressed in mucosal epithelia and important agents of innate immunity, act as antimicrobial and chemotactic agents at mucosal barriers. In this perspective, we present evidence supporting a novel strategy by which the oral bacterium

Indexed as

beta-defensinFAD-IF. nucleatumP. gingivalissymbiosis

Identifiers

PMID29535688
PMCPMC5835341
OpenAlexW2791652798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.