Evidence map›Paper›PMID 29535678›Full record

ArticleFrontiers in neurology2018

Progressively Disrupted Brain Functional Connectivity Network in Subcortical Ischemic Vascular Cognitive Impairment Patients.

Linqiong Sang, Lin Chen, Li Wang, Jingna Zhang, Ye Zhang, Pengyue Li, Chuanming Li, Mingguo Qiu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  5. Language Impairment in Vascular Dementia: A Clinical Review.Journal of geriatric psychiatry and neurology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Linqiong SangDepartment of Medical Imaging, College of Biomedical Engineering, Third Military Medical University, Chongqing, China.
Lin ChenDepartment of Psychology, Third Military Medical University, Chongqing, China.
Li WangDepartment of Medical Imaging, College of Biomedical Engineering, Third Military Medical University, Chongqing, China.
Jingna ZhangDepartment of Medical Imaging, College of Biomedical Engineering, Third Military Medical University, Chongqing, China.
Ye ZhangDepartment of Medical Imaging, College of Biomedical Engineering, Third Military Medical University, Chongqing, China.
Pengyue LiDepartment of Medical Imaging, College of Biomedical Engineering, Third Military Medical University, Chongqing, China.
Chuanming LiDepartment of Radiology, Southwest Hospital, Third Military Medical University, Chongqing, China.
Mingguo QiuDepartment of Medical Imaging, College of Biomedical Engineering, Third Military Medical University, Chongqing, China.
Army Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive impairment caused by subcortical ischemic vascular disease (SIVD) has been elucidated by many neuroimaging studies. However, little is known regarding the changes in brain functional connectivity networks in relation to the severity of cognitive impairment in SIVD. In the present study, 20 subcortical ischemic vascular cognitive impairment no dementia patients (SIVCIND) and 20 dementia patients (SIVaD) were enrolled; additionally, 19 normal controls were recruited. Each participant underwent a resting-state functional MRI scan. Whole-brain functional networks were analyzed with graph theory and network-based statistics (NBS) to study the functional organization of networks and find alterations in functional connectivity among brain regions. After adjustments for age, gender, and duration of formal education, there were significant group differences for two network functional organization indices, global efficiency and local efficiency, which decreased (NC > SIVCIND > SIVaD) as cognitive impairment worsened. Between-group differences in functional connectivity (NBS corrected,

Indexed as

functional connectionsgraph theoretical analysisnetwork-based statisticssubcortical ischemic vascular cognitive impairmenttopological organization

Identifiers

PMID29535678
PMCPMC5834750
OpenAlexW2791122882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.