Evidence map›Paper›PMID 29535636›Full record

ArticleFrontiers in physiology2018

Short-Term Sustained Hypoxia Elevates Basal and Hypoxia-Induced Ventilation but Not the Carotid Body Chemoreceptor Activity in Rats.

Karine C Flor, Elaine F Silva, Miguel F Menezes, Gustavo R Pedrino, Eduardo Colombari, Daniel B Zoccal

Abstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Hypoxia augments TRPM3-mediated calcium influx in vagal sensory neurons.Autonomic neuroscience : basic & clinical · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Karine C FlorDepartment of Physiology and Pathology, São Paulo State University, Araraquara, Brazil.
Elaine F SilvaDepartment of Physiological Sciences, Federal University of Goiás, Goiânia, Brazil.
Miguel F MenezesDepartment of Physiology and Pathology, São Paulo State University, Araraquara, Brazil.
Gustavo R PedrinoDepartment of Physiological Sciences, Federal University of Goiás, Goiânia, Brazil.
Eduardo ColombariDepartment of Physiology and Pathology, São Paulo State University, Araraquara, Brazil.
Daniel B ZoccalDepartment of Physiology and Pathology, São Paulo State University, Araraquara, Brazil.

Funding

CRCNS: Modeling the respiratory-sympathetic coupling in neurogenic hypertensionR01AT008632 · NCCIH · INDIANA UNIVERSITY INDIANAPOLIS · PI MOLKOV, YAROSLAV · 2015 to 2019
$1.4M
NCCIH NIH HHS R01 AT008632
6 · The paper itself

Abstract

Exposure to chronic sustained hypoxia (SH), as experienced in high altitudes, elicits an increase in ventilation, named ventilatory acclimatization to hypoxia (VAH). We previously showed that rats exposed to short-term (24 h) SH exhibit enhanced abdominal expiratory motor activity at rest, accompanied by augmented baseline sympathetic vasoconstrictor activity. In the present study, we investigated whether the respiratory and sympathetic changes elicited by short-term SH are accompanied by carotid body chemoreceptor sensitization. Juvenile male Holtzman rats (60-80 g) were exposed to SH (10% O

Indexed as

active expirationcarotid bodychemoreceptorhypoxic ventilatory responsesympathetic activityventilatory acclimatization

Identifiers

PMID29535636
PMCPMC5835044

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.