Evidence map›Paper›PMID 29535538›Full record

ArticleOncoTargets and therapy2018

Effects of propofol-based total intravenous anesthesia on gastric cancer: a retrospective study.

Xiaoyu Zheng, Yu Wang, Linlin Dong, Su Zhao, Liping Wang, Hong Chen, Yang Xu, Guonian Wang

Open access · goldAbstract read
In one paragraph

Article in OncoTargets and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 3 pooled it
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 3 syntheses or guidelines pooled it, 106 citations in OpenAlex.

  1. Pooled it
  2. Association Between Anesthesia Delivered During Tumor Resection and Cancer Survival: a Systematic Review of a Mixed Picture with Constant Themes.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Pooled it
  3. Anesthetic technique and cancer outcomes: a meta-analysis of total intravenous versus volatile anesthesia.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2019
    Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Review
  8. Does anesthesia choice shape oncologic destiny in gastric cancer surgery?World journal of gastrointestinal oncology · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Anesthesia and cancer recurrence: a narrative review.Anesthesia and pain medicine · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Anesthesia-related postoperative oncological surgical outcomes: a comparison of total intravenous anesthesia and volatile anesthesia. A meta-analysis.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xiaoyu ZhengDepartment of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, China.
Yu WangDepartment of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, China.
Linlin DongDepartment of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, China.
Su ZhaoDepartment of Thoracic Surgery, Harbin Medical University Cancer Hospital, Harbin, China.
Liping WangDepartment of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, China.
Hong ChenDepartment of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, China.
Yang XuDepartment of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, China.
Guonian WangDepartment of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, China.
Harbin Medical University · CNThird Affiliated Hospital of Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral kinds of cancer surgeries with propofol-based total intravenous anesthesia (TIVA) have been shown to have better outcomes than those with sevoflurane-based inhalational anesthesia (INHA). However, the effects of this anesthetic technique have not been investigated in patients with gastric cancer. In this study, the authors retrospectively examined the link between the choice of anesthetic technique and overall survival in patients undergoing gastric cancer resection.

methodsWe conducted a retrospective analysis of the database of all patients undergoing gastric cancer resection for gastric cancer between 2007 and 2012. Patients who received TIVA or INHA were administered patient-controlled intravenous analgesia for 72-120 hours postoperatively. Survival was estimated using the Kaplan-Meier log-rank test, and associations between anesthetic technique and outcomes were analyzed using Cox proportional hazards regressions after propensity matching.

resultsA total of 2,856 anesthetics using INHA or TIVA were delivered in the study period. After propensity matching, 897 patients remained in each group. According to Kaplan-Meier analysis, the use of TIVA was associated with improved survival (

conclusionThese results indicate that TIVA may be associated with improved survival in gastric cancer patients who undergo resection.

Indexed as

anesthesiagastric canceroverall survivalpatient-controlled analgesiapropofolsevoflurane

Identifiers

PMID29535538
PMCPMC5840299
OpenAlexW2793402648

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.