ArticleTherapeutics and clinical risk management2018
Clinical and economic burden of procedural sedation-related adverse events and their outcomes: analysis from five countries.
Article in Therapeutics and clinical risk management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Antihistamine effects and safety of fexofenadine: a systematic review and Meta-analysis of randomized controlled trials.BMC pharmacology & toxicology · 2019Pooled it
- Sedation reversal trends at outpatient ambulatory endoscopic centerWorld journal of gastrointestinal endoscopy · 2024Trial
- Comparing a Virtual Reality-Based Simulation App (VR-MRI) With a Standard Preparatory Manual and Child Life Program for Improving Success and Reducing Anxiety During Pediatric Medical Imaging: Randomized Clinical Trial.Journal of medical Internet research · 2021Trial
- Preoperative Imaging for Cochlear Implantation: A Global Consensus.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026Article
- Early budget impact analysis of magnetic balloon technology for facilitating the completion of difficult colonoscopies.Cost effectiveness and resource allocation : C/E · 2025Article
- Does capnography improve safety in moderate-deep sedation for gastrointestinal endoscopic procedures provided by anaesthesiologists? A prospective cohort study.Journal of clinical monitoring and computing · 2025Article
- Cryoballoon Ablation With the POLARx FIT or the Arctic Front Advance Pro for Paroxysmal Atrial Fibrillation: A Health Economic Analysis.Journal of health economics and outcomes research · 2025Article
- Evaluating Remimazolam for Procedural Sedation.Current neuropharmacology · 2025Review
- Patient Safety during Propofol Sedation before and after Implementation of Capnography Monitoring.Journal of clinical medicine · 2023Article
- Up-to-date literature review and issues of sedation during digestive endoscopy.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2023Review
- Cost-effectiveness of mechanical thromboprophylaxis for cesarean deliveries in Brazil.PloS one · 2023Article
- Service Evaluation of the Impact of Capnography on the Safety of Procedural Sedation.Frontiers in medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies have reported on the incidence of sedation-related adverse events (AEs), but little is known about their impact on health care costs and resource use.
methodsHealth care providers and payers in five countries were recruited for an online survey by independent administrators to ensure that investigators and respondents were blinded to each other. Surveys were conducted in the local language and began with a "screener" to ensure that respondents had relevant expertise and experience. Responses were analyzed using Excel and R, with the Dixon's
resultsResponses were received from 101 providers and 26 payers, the majority having >5 years of experience. At a minimum, the respondents performed a total of 3,430 procedural sedations per month. All AEs detailed occurred in clinical practice in the last year and were reported to cause procedural delays and cancellations in some patients. Standard procedural sedation costs ranged from €74 (Germany) to $2,300 (US). Respondents estimated that AEs would increase costs by between 16% (Italy) and 179% (US). Hypotension was reported as the most commonly observed AE with an associated global mean cost (interquartile range) of $43 ($27-$68). Other frequent AEs, including mild hypotension, bradycardia, tachycardia, mild oxygen desaturation, hypertension, and brief apnea, were estimated to increase health care spending on procedural sedation by $2.2 billion annually in the US.
conclusionAll sedation-related AEs can increase health care costs and result in substantial delays or cancellations of subsequent procedures. The prevention of even minor AEs during procedural sedation may be crucial to ensuring its value as a health care service.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.