Evidence map›Paper›PMID 29535521›Full record

ArticleInternational journal of nanomedicine2018

The evaluation of zinc and copper content in tooth enamel without any pathological changes - an in vitro study.

Elzbieta Klimuszko, Karolina Orywal, Teresa Sierpinska, Jarosław Sidun, Maria Golebiewska

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Elzbieta KlimuszkoDepartment of Prosthetic Dentistry, Medical University of Bialystok, Bialystok, Poland.
Karolina OrywalLaboratory of Biochemical Diagnostics Department, Medical University of Bialystok, Bialystok, Poland.
Teresa SierpinskaDepartment of Prosthetic Dentistry, Medical University of Bialystok, Bialystok, Poland.
Jarosław SidunDepartment of Materials Science and Biomedical Engineering, Bialystok University of Technology, Bialystok, Poland.
Maria GolebiewskaDepartment of Prosthetic Dentistry, Medical University of Bialystok, Bialystok, Poland.
Bialystok University of Technology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objectives of the study were to evaluate the content of copper and zinc in individual layers of tooth enamel and to analyze the relationships between the study minerals in individual layers of tooth enamel. PATIENTS AND

methodsFifteen human permanent teeth were cut off every 150 μm alongside the labial surface. Acid biopsy of each layer was performed. The zinc content was determined using the air-acetylene flame method. The copper content was determined using the electrothermal technique with argon.

resultsThe mean zinc concentrations increased significantly starting from the outer enamel surface, with the maximum concentration in the 150-300 μm layer. The mean copper concentrations increased substantially from the outer enamel surface to a depth of 150 μm, and then a slight downward trend of this mineral levels was seen, down to a depth of 450 μm. Strong positive correlation was found between the zinc and copper concentrations at depths of 150-300, 450-600 and 600-750 μm.

conclusionThe levels of zinc and copper in the outer enamel layers may have an effect on the increased content of unipolar minerals at deeper enamel layers. The content of the study elements determined may reflect the process of mineralization and maturation of enamel in the pre-eruption period.

Indexed as

AdolescentCopperDental EnamelHumansToothYoung AdultZincCopperZinccopperenamelzinc

Identifiers

PMID29535521
PMCPMC5841334
OpenAlexW2793507690

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.