ArticleStroke2018
Atrial Cardiopathy and the Risk of Ischemic Stroke in the CHS (Cardiovascular Health Study).
Abstract read
In one paragraph
Article in Stroke, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 3 pooled it
11.8field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
82 citing papers in PubMed, 3 syntheses or guidelines pooled it, 152 citations in OpenAlex.
- Atrial cardiomyopathy and incident ischemic stroke risk: a systematic review and meta-analysis.Journal of neurology · 2023Pooled it
- Patterns of Infarction on MRI in Patients With Acute Ischemic Stroke and Cardio-Embolism: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2020Pooled it
- Association of Intracranial Hemorrhage Risk With Non-Vitamin K Antagonist Oral Anticoagulant Use vs Aspirin Use: A Systematic Review and Meta-analysis.JAMA neurology · 2018Pooled it
- History of Cancer and Atrial Cardiopathy: A Secondary Analysis of the ARCADIA Clinical Trial.Journal of the American Heart Association · 2025Trial
- Atrial Myopathy and Ischemic Stroke in Heart Failure With Preserved Ejection Fraction.The American journal of cardiology · 2023Trial
- Recurrent Stroke With Rivaroxaban Compared With Aspirin According to Predictors of Atrial Fibrillation: Secondary Analysis of the NAVIGATE ESUS Randomized Clinical Trial.JAMA neurology · 2019Trial
- The perspective of combining pulsed field ablation and left atrial appendage closure.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Review
- Beyond Sinus Rhythm: Rhythm Control and Mechanism-Based Secondary Prevention in Atrial Fibrillation-Related Stroke.Journal of atherosclerosis and thrombosis · 2026Review
- The clinical pathophysiology of atrial fibrillation: outstanding questions from bedside to bench and back.Physiological reviews · 2026Review
- Device-Detected Atrial Fibrillation: Why Time-Based Thresholds Are No Longer Fit for Purpose.Journal of clinical medicine · 2026Article
- Atrial Cardiomyopathy Detected by Electrocardiogram: Association with Stroke in a Brazilian Electronic Cohort.Arquivos brasileiros de cardiologia · 2026Article
- Atrial cardiopathy and thrombus composition in acute ischemic stroke: histological examination reveals insights into etiology and outcomes.Journal of thrombosis and thrombolysis · 2026Article
- Causality of atrial fibrillation and left atrial traits: Genetic and epigenetic perspectives.Heart rhythm O2 · 2026Article
- Heart-brain axis pathophysiological understanding and clinical impact.Frontiers in cardiovascular medicine · 2026Review
- Predictive factors for new-onset atrial fibrillation in patients with embolic stroke of undetermined source and left atrial enlargement - development of a risk score.Cardiology journal · 2026Observational
- Are the Direct Oral Anticoagulants Better Than Warfarin for the Prevention and Treatment of Stroke and Atrial Fibrillation?Handbook of experimental pharmacology · 2026Review
- The Electrocardiogram as a Window into Atrial Pathology: Insights from a Large Brazilian Cohort on Atrial Cardiomyopathy and Stroke.Arquivos brasileiros de cardiologia · 2026Article
- Renal Function, Atrial Cardiopathy, and Their Joint Association with Mortality in the General Population.Journal of clinical medicine · 2025Article
- Subtle signs of atrial cardiomyopathy and left ventricular diastolic dysfunction are associated with reduced cognitive function: results from the Hamburg City Health Study.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Arrhythmia-Induced Cardiomyopathy in Atrial Fibrillation: Pathogenesis, Diagnosis, and Treatment.Life (Basel, Switzerland) · 2025Review
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 7 institutions in 1 country.
Hooman KamelFrom the Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute (H.K.) and Division of Cardiology (P.M.O.), Weill Cornell Medical College, New York, NY; Department of Biostatistics (T.M.B.), Department of Medicine (K.K.P., W.T.L.), Department of Epidemiology, Cardiovascular Health Research Unit (S.R.H.), Department of Biostatistics, Collaborative Health Studies Coordinating Center (R.A.K.), Department of Neurology (W.T.L.), and Department of Epidemiology (W.T.L.), University of Washington, Seattle; Department of Neurology, College of Physicians and Surgeons (M.S.V.E.) and Department of Epidemiology, Mailman School of Public Health (M.S.V.E.), Columbia University, New York, NY; Department of Health Science, Brigham Young University, Provo, UT (E.L.T.); Cardiovascular Division, Washington University School of Medicine, St. Louis, MO (P.K.S.); Inova Heart and Vascular Institute, Falls Church, VA (C.d.); Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); and Epidemiological Cardiology Research Center, Wake Forest University School of Medicine, Winston-Salem, NC (E.Z.S.). hok9010@med.cornell.edu.
Traci M BartzFrom the Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute (H.K.) and Division of Cardiology (P.M.O.), Weill Cornell Medical College, New York, NY; Department of Biostatistics (T.M.B.), Department of Medicine (K.K.P., W.T.L.), Department of Epidemiology, Cardiovascular Health Research Unit (S.R.H.), Department of Biostatistics, Collaborative Health Studies Coordinating Center (R.A.K.), Department of Neurology (W.T.L.), and Department of Epidemiology (W.T.L.), University of Washington, Seattle; Department of Neurology, College of Physicians and Surgeons (M.S.V.E.) and Department of Epidemiology, Mailman School of Public Health (M.S.V.E.), Columbia University, New York, NY; Department of Health Science, Brigham Young University, Provo, UT (E.L.T.); Cardiovascular Division, Washington University School of Medicine, St. Louis, MO (P.K.S.); Inova Heart and Vascular Institute, Falls Church, VA (C.d.); Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); and Epidemiological Cardiology Research Center, Wake Forest University School of Medicine, Winston-Salem, NC (E.Z.S.).
Mitchell S V ElkindFrom the Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute (H.K.) and Division of Cardiology (P.M.O.), Weill Cornell Medical College, New York, NY; Department of Biostatistics (T.M.B.), Department of Medicine (K.K.P., W.T.L.), Department of Epidemiology, Cardiovascular Health Research Unit (S.R.H.), Department of Biostatistics, Collaborative Health Studies Coordinating Center (R.A.K.), Department of Neurology (W.T.L.), and Department of Epidemiology (W.T.L.), University of Washington, Seattle; Department of Neurology, College of Physicians and Surgeons (M.S.V.E.) and Department of Epidemiology, Mailman School of Public Health (M.S.V.E.), Columbia University, New York, NY; Department of Health Science, Brigham Young University, Provo, UT (E.L.T.); Cardiovascular Division, Washington University School of Medicine, St. Louis, MO (P.K.S.); Inova Heart and Vascular Institute, Falls Church, VA (C.d.); Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); and Epidemiological Cardiology Research Center, Wake Forest University School of Medicine, Winston-Salem, NC (E.Z.S.).
Peter M OkinFrom the Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute (H.K.) and Division of Cardiology (P.M.O.), Weill Cornell Medical College, New York, NY; Department of Biostatistics (T.M.B.), Department of Medicine (K.K.P., W.T.L.), Department of Epidemiology, Cardiovascular Health Research Unit (S.R.H.), Department of Biostatistics, Collaborative Health Studies Coordinating Center (R.A.K.), Department of Neurology (W.T.L.), and Department of Epidemiology (W.T.L.), University of Washington, Seattle; Department of Neurology, College of Physicians and Surgeons (M.S.V.E.) and Department of Epidemiology, Mailman School of Public Health (M.S.V.E.), Columbia University, New York, NY; Department of Health Science, Brigham Young University, Provo, UT (E.L.T.); Cardiovascular Division, Washington University School of Medicine, St. Louis, MO (P.K.S.); Inova Heart and Vascular Institute, Falls Church, VA (C.d.); Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); and Epidemiological Cardiology Research Center, Wake Forest University School of Medicine, Winston-Salem, NC (E.Z.S.).
Evan L ThackerFrom the Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute (H.K.) and Division of Cardiology (P.M.O.), Weill Cornell Medical College, New York, NY; Department of Biostatistics (T.M.B.), Department of Medicine (K.K.P., W.T.L.), Department of Epidemiology, Cardiovascular Health Research Unit (S.R.H.), Department of Biostatistics, Collaborative Health Studies Coordinating Center (R.A.K.), Department of Neurology (W.T.L.), and Department of Epidemiology (W.T.L.), University of Washington, Seattle; Department of Neurology, College of Physicians and Surgeons (M.S.V.E.) and Department of Epidemiology, Mailman School of Public Health (M.S.V.E.), Columbia University, New York, NY; Department of Health Science, Brigham Young University, Provo, UT (E.L.T.); Cardiovascular Division, Washington University School of Medicine, St. Louis, MO (P.K.S.); Inova Heart and Vascular Institute, Falls Church, VA (C.d.); Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); and Epidemiological Cardiology Research Center, Wake Forest University School of Medicine, Winston-Salem, NC (E.Z.S.).
Kristen K PattonFrom the Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute (H.K.) and Division of Cardiology (P.M.O.), Weill Cornell Medical College, New York, NY; Department of Biostatistics (T.M.B.), Department of Medicine (K.K.P., W.T.L.), Department of Epidemiology, Cardiovascular Health Research Unit (S.R.H.), Department of Biostatistics, Collaborative Health Studies Coordinating Center (R.A.K.), Department of Neurology (W.T.L.), and Department of Epidemiology (W.T.L.), University of Washington, Seattle; Department of Neurology, College of Physicians and Surgeons (M.S.V.E.) and Department of Epidemiology, Mailman School of Public Health (M.S.V.E.), Columbia University, New York, NY; Department of Health Science, Brigham Young University, Provo, UT (E.L.T.); Cardiovascular Division, Washington University School of Medicine, St. Louis, MO (P.K.S.); Inova Heart and Vascular Institute, Falls Church, VA (C.d.); Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); and Epidemiological Cardiology Research Center, Wake Forest University School of Medicine, Winston-Salem, NC (E.Z.S.).
Phyllis K SteinFrom the Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute (H.K.) and Division of Cardiology (P.M.O.), Weill Cornell Medical College, New York, NY; Department of Biostatistics (T.M.B.), Department of Medicine (K.K.P., W.T.L.), Department of Epidemiology, Cardiovascular Health Research Unit (S.R.H.), Department of Biostatistics, Collaborative Health Studies Coordinating Center (R.A.K.), Department of Neurology (W.T.L.), and Department of Epidemiology (W.T.L.), University of Washington, Seattle; Department of Neurology, College of Physicians and Surgeons (M.S.V.E.) and Department of Epidemiology, Mailman School of Public Health (M.S.V.E.), Columbia University, New York, NY; Department of Health Science, Brigham Young University, Provo, UT (E.L.T.); Cardiovascular Division, Washington University School of Medicine, St. Louis, MO (P.K.S.); Inova Heart and Vascular Institute, Falls Church, VA (C.d.); Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); and Epidemiological Cardiology Research Center, Wake Forest University School of Medicine, Winston-Salem, NC (E.Z.S.).
Christopher R deFilippiFrom the Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute (H.K.) and Division of Cardiology (P.M.O.), Weill Cornell Medical College, New York, NY; Department of Biostatistics (T.M.B.), Department of Medicine (K.K.P., W.T.L.), Department of Epidemiology, Cardiovascular Health Research Unit (S.R.H.), Department of Biostatistics, Collaborative Health Studies Coordinating Center (R.A.K.), Department of Neurology (W.T.L.), and Department of Epidemiology (W.T.L.), University of Washington, Seattle; Department of Neurology, College of Physicians and Surgeons (M.S.V.E.) and Department of Epidemiology, Mailman School of Public Health (M.S.V.E.), Columbia University, New York, NY; Department of Health Science, Brigham Young University, Provo, UT (E.L.T.); Cardiovascular Division, Washington University School of Medicine, St. Louis, MO (P.K.S.); Inova Heart and Vascular Institute, Falls Church, VA (C.d.); Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); and Epidemiological Cardiology Research Center, Wake Forest University School of Medicine, Winston-Salem, NC (E.Z.S.).
Rebecca F GottesmanFrom the Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute (H.K.) and Division of Cardiology (P.M.O.), Weill Cornell Medical College, New York, NY; Department of Biostatistics (T.M.B.), Department of Medicine (K.K.P., W.T.L.), Department of Epidemiology, Cardiovascular Health Research Unit (S.R.H.), Department of Biostatistics, Collaborative Health Studies Coordinating Center (R.A.K.), Department of Neurology (W.T.L.), and Department of Epidemiology (W.T.L.), University of Washington, Seattle; Department of Neurology, College of Physicians and Surgeons (M.S.V.E.) and Department of Epidemiology, Mailman School of Public Health (M.S.V.E.), Columbia University, New York, NY; Department of Health Science, Brigham Young University, Provo, UT (E.L.T.); Cardiovascular Division, Washington University School of Medicine, St. Louis, MO (P.K.S.); Inova Heart and Vascular Institute, Falls Church, VA (C.d.); Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); and Epidemiological Cardiology Research Center, Wake Forest University School of Medicine, Winston-Salem, NC (E.Z.S.).
Susan R HeckbertFrom the Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute (H.K.) and Division of Cardiology (P.M.O.), Weill Cornell Medical College, New York, NY; Department of Biostatistics (T.M.B.), Department of Medicine (K.K.P., W.T.L.), Department of Epidemiology, Cardiovascular Health Research Unit (S.R.H.), Department of Biostatistics, Collaborative Health Studies Coordinating Center (R.A.K.), Department of Neurology (W.T.L.), and Department of Epidemiology (W.T.L.), University of Washington, Seattle; Department of Neurology, College of Physicians and Surgeons (M.S.V.E.) and Department of Epidemiology, Mailman School of Public Health (M.S.V.E.), Columbia University, New York, NY; Department of Health Science, Brigham Young University, Provo, UT (E.L.T.); Cardiovascular Division, Washington University School of Medicine, St. Louis, MO (P.K.S.); Inova Heart and Vascular Institute, Falls Church, VA (C.d.); Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); and Epidemiological Cardiology Research Center, Wake Forest University School of Medicine, Winston-Salem, NC (E.Z.S.).
Richard A KronmalFrom the Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute (H.K.) and Division of Cardiology (P.M.O.), Weill Cornell Medical College, New York, NY; Department of Biostatistics (T.M.B.), Department of Medicine (K.K.P., W.T.L.), Department of Epidemiology, Cardiovascular Health Research Unit (S.R.H.), Department of Biostatistics, Collaborative Health Studies Coordinating Center (R.A.K.), Department of Neurology (W.T.L.), and Department of Epidemiology (W.T.L.), University of Washington, Seattle; Department of Neurology, College of Physicians and Surgeons (M.S.V.E.) and Department of Epidemiology, Mailman School of Public Health (M.S.V.E.), Columbia University, New York, NY; Department of Health Science, Brigham Young University, Provo, UT (E.L.T.); Cardiovascular Division, Washington University School of Medicine, St. Louis, MO (P.K.S.); Inova Heart and Vascular Institute, Falls Church, VA (C.d.); Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); and Epidemiological Cardiology Research Center, Wake Forest University School of Medicine, Winston-Salem, NC (E.Z.S.).
Elsayed Z SolimanFrom the Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute (H.K.) and Division of Cardiology (P.M.O.), Weill Cornell Medical College, New York, NY; Department of Biostatistics (T.M.B.), Department of Medicine (K.K.P., W.T.L.), Department of Epidemiology, Cardiovascular Health Research Unit (S.R.H.), Department of Biostatistics, Collaborative Health Studies Coordinating Center (R.A.K.), Department of Neurology (W.T.L.), and Department of Epidemiology (W.T.L.), University of Washington, Seattle; Department of Neurology, College of Physicians and Surgeons (M.S.V.E.) and Department of Epidemiology, Mailman School of Public Health (M.S.V.E.), Columbia University, New York, NY; Department of Health Science, Brigham Young University, Provo, UT (E.L.T.); Cardiovascular Division, Washington University School of Medicine, St. Louis, MO (P.K.S.); Inova Heart and Vascular Institute, Falls Church, VA (C.d.); Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); and Epidemiological Cardiology Research Center, Wake Forest University School of Medicine, Winston-Salem, NC (E.Z.S.).
W T LongstrethFrom the Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute (H.K.) and Division of Cardiology (P.M.O.), Weill Cornell Medical College, New York, NY; Department of Biostatistics (T.M.B.), Department of Medicine (K.K.P., W.T.L.), Department of Epidemiology, Cardiovascular Health Research Unit (S.R.H.), Department of Biostatistics, Collaborative Health Studies Coordinating Center (R.A.K.), Department of Neurology (W.T.L.), and Department of Epidemiology (W.T.L.), University of Washington, Seattle; Department of Neurology, College of Physicians and Surgeons (M.S.V.E.) and Department of Epidemiology, Mailman School of Public Health (M.S.V.E.), Columbia University, New York, NY; Department of Health Science, Brigham Young University, Provo, UT (E.L.T.); Cardiovascular Division, Washington University School of Medicine, St. Louis, MO (P.K.S.); Inova Heart and Vascular Institute, Falls Church, VA (C.d.); Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD (R.F.G.); and Epidemiological Cardiology Research Center, Wake Forest University School of Medicine, Winston-Salem, NC (E.Z.S.).
Columbia University · USAlaska Heart and Vascular Institute · USJohns Hopkins Medicine · USWake Forest University · USBrigham Young University · USJohns Hopkins University · USUniversity of Washington · US
Funding
Exceptional Survival: Trajectories to Functional Aging (CHS All Stars)R01AG023629 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NEWMAN, ANNE B. · 2004 to 2016
$9.5MCHS research resources for the cardiovascular health of older adultsU01HL130114 · NHLBI · UNIVERSITY OF WASHINGTON · PI BURKE, GREGORY L, KRONMAL, RICHARD A · 2016 to 2019
$6.6MCHS Events Follow-up StudyU01HL080295 · NHLBI · UNIVERSITY OF WASHINGTON · PI PSATY, BRUCE M · 2005 to 2008
$4.6MAtrial Fibrillation Precursors May Be Novel Stroke Risk FactorsK23NS082367 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI KAMEL, HOOMAN · 2013 to 2017
$937kCORONARY HEART DISEASE &STROKE IN PEOPLE AGED 65-84N01HC085081 · HC · JOHNS HOPKINS UNIVERSITY · PI FRIED, LINDA P · 1988 to 2000
–CORONARY HEART DISEASE AND STROKE IN PEOPLE AGED 65-84N01HC085082 · HC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KULLER, LEWIS H · 1988 to 2000
–CORONARY HEART DISEASE &STROKE IN PEOPLE AGED 65-84N01HC085083 · HC · UNIVERSITY OF CALIFORNIA DAVIS · PI ROBBINS, JOHN A · 1988 to 1999
–CENTRAL BLOOD ANALYSIS LABORATORY FOR CHSN01HC085086 · HC · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI TRACY, RUSSELL P · 1988 to 2000
–CORONARY HEART DISEASE &STROKE IN THE ELDERLYN01HC085080 · HC · WAKE FOREST UNIVERSITY · PI BURKE, GREGORY L · 1988 to 2000
–CORONARY HEART DISEASE &STROKE IN PEOPLE AGED 65 TO 84N01HC085079 · HC · UNIVERSITY OF WASHINGTON · 1988 to 2005
–CHS-Transition Phase -268055222-268055222N01HC055222 · HC · UNIVERSITY OF WASHINGTON · PI KRONMAL, RICHARD A · 2005 to 2006
–NHLBI NIH HHS N01 HC055222NHLBI NIH HHS N01 HC085079NHLBI NIH HHS N01 HC085080NHLBI NIH HHS N01 HC085081NHLBI NIH HHS N01 HC085082NHLBI NIH HHS N01 HC085083NHLBI NIH HHS N01 HC085086NHLBI NIH HHS U01 HL080295NHLBI NIH HHS U01 HL130114NIA NIH HHS R01 AG023629NINDS NIH HHS K23 NS082367
Abstract
background and purposeEmerging evidence suggests that an underlying atrial cardiopathy may result in thromboembolism before atrial fibrillation (AF) develops. We examined the association between various markers of atrial cardiopathy and the risk of ischemic stroke.
methodsThe CHS (Cardiovascular Health Study) prospectively enrolled community-dwelling adults ≥65 years of age. For this study, we excluded participants diagnosed with stroke or AF before baseline. Exposures were several markers of atrial cardiopathy: baseline P-wave terminal force in ECG lead V
resultsAmong 3723 participants who were free of stroke and AF at baseline and who had data on all atrial cardiopathy markers, 585 participants (15.7%) experienced an incident ischemic stroke during a median 12.9 years of follow-up. When all atrial cardiopathy markers were combined in 1 Cox model, we found significant associations with stroke for P-wave terminal force in ECG lead V
conclusionsIn addition to clinically apparent AF, other evidence of abnormal atrial substrate is associated with subsequent ischemic stroke. This finding is consistent with the hypothesis that thromboembolism from the left atrium may occur in the setting of several different manifestations of atrial disease.
Indexed as
AgedAged, 80 and overAtrial FibrillationBrain IschemiaCohort StudiesEchocardiographyElectrocardiographyFemaleFollow-Up StudiesHeart AtriaHeart DiseasesHumansIncidenceMaleNatriuretic Peptide, BrainOrgan SizeNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)adultatrial fibrillationcardiomyopathiesrisk factorsthromboembolism
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